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心房黏液瘤:全国发病率、诊断与外科治疗

Atrial myxoma: national incidence, diagnosis and surgical management.

作者信息

MacGowan S W, Sidhu P, Aherne T, Luke D, Wood A E, Neligan M C, McGovern E

机构信息

National Cardiac Surgery Unit, Mater Misericordiae Hospital, Dublin.

出版信息

Ir J Med Sci. 1993 Jun;162(6):223-6. doi: 10.1007/BF02945200.

Abstract

Despite being the most common benign intracardiac tumour with an excellent prognosis after surgical excision the incidence of atrial myxoma (except at autopsy) is unknown. We reviewed all patients admitted to the National Cardiac Surgery Unit (n = 26) with an atrial myxoma over a fifteen year period (1977-1991) to compile national incidence data and assess pre-operative diagnosis, management, surgical technique, and outcome. Preoperative symptoms were: congestive cardiac failure (12 patients), embolism (8 patients), constitutional (3 patients), asymptomatic (2 patients) and tachyarrhythmia (1 patient). The diagnosis was confirmed by 2D echocardiography alone in thirteen patients and by a combination of echocardiography and angiography in thirteen patients. At operation the site of the tumour was left atrial in 24 patients and bi-atrial in two patients. All cases were confirmed by histology. All patients made a good post-operative recovery, although one patient survived a pulmonary embolus and one patient developed a deep venous thrombosis. There has been one late death (five months after surgery) from a cerebrovascular accident. Serial echocardiography has revealed one recurrence to date (8 years after surgery). The surgical incidence of these tumours in the Republic of Ireland over the study period was 0.5 atrial myxomas/million population/year. Although rare atrial myxomas are the most important cardiac tumours to diagnose as the results from surgery are excellent.

摘要

尽管心房黏液瘤是最常见的心脏良性肿瘤,手术切除后预后良好,但心房黏液瘤的发病率(尸检除外)尚不清楚。我们回顾了在15年期间(1977 - 1991年)入住国家心脏外科病房的所有心房黏液瘤患者(n = 26例),以汇编全国发病率数据,并评估术前诊断、治疗、手术技术和结果。术前症状包括:充血性心力衰竭(12例)、栓塞(8例)、全身症状(3例)、无症状(2例)和快速心律失常(1例)。13例患者仅通过二维超声心动图确诊,13例患者通过超声心动图和血管造影联合确诊。手术时,24例患者肿瘤位于左心房,2例患者位于双心房。所有病例均经组织学证实。所有患者术后恢复良好,尽管1例患者发生肺栓塞幸存,1例患者发生深静脉血栓形成。有1例患者术后5个月死于脑血管意外。迄今为止,系列超声心动图检查发现1例复发(术后8年)。在研究期间,爱尔兰共和国这些肿瘤的手术发病率为每年每百万人口0.5例心房黏液瘤。尽管罕见,但心房黏液瘤是最重要的需诊断的心脏肿瘤,因为手术效果极佳。

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