Al-Mamgani Abrahim, Baartman Lizette, Baaijens Margreet, de Pree Ilse, Incrocci Luca, Levendag Peter C
Department of Radiation Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Groene Hilledijk 301, Rotterdam, The Netherlands.
Int J Clin Oncol. 2008 Aug;13(4):369-72. doi: 10.1007/s10147-007-0749-8. Epub 2008 Aug 15.
We report a case of esophageal cancer with symptomatic metastases to the heart; the patient was treated with short-course radiotherapy with good symptomatic relief. We reviewed the current literature regarding the epidemiology, clinical presentation, diagnostic tools, treatment modalities, and the prognosis of cardiac metastases. In this report we summarize the most recent autopsy studies (published between 1975 and 2007), in which we found an autopsy incidence of cardiac metastases of 2.3% among the general population, while the incidence among autopsies of cancer patients was 7.1%. Therefore, we share the opinion with others that there has been an increase in the incidence of cardiac metastases among cancer patients diagnosed after 1970, in comparison with the reported incidences in older series before 1970 (7.1% vs 3.8%; Kruskal-Wallis rank test; P = 0.039). Special attention was given to the role of radiotherapy in the management of cardiac metastases.
我们报告一例伴有心脏症状性转移的食管癌病例；该患者接受了短程放疗，症状得到明显缓解。我们回顾了当前关于心脏转移瘤的流行病学、临床表现、诊断工具、治疗方式及预后的文献。在本报告中，我们总结了最近的尸检研究（发表于1975年至2007年之间），我们发现一般人群中心脏转移瘤的尸检发生率为2.3%，而癌症患者尸检中的发生率为7.1%。因此，我们与其他人观点一致，即与1970年以前旧系列报道的发生率相比（7.1%对3.8%；Kruskal-Wallis秩和检验；P = 0.039），1970年以后诊断的癌症患者中心脏转移瘤的发生率有所增加。我们特别关注了放疗在心脏转移瘤治疗中的作用。
