Ayers J W, Seiler J C
J Reprod Med. 1984 Jan;29(1):67-70.
Depressive illness has been associated with reversible abnormalities in the pituitary response of growth hormone, prolactin, and ACTH-cortisol. We saw similar neuroendocrine abnormalities in a patient with pseudocyesis. Normalization of the hormonal responses occurred with resolution of the pseudocyesis. Ovarian responsiveness to HCG suggests pseudocyesis to be of central hypothalamic-pituitary origin similar to polycystic ovarian disease, with neuroendocrine data consistent with reversible depression. In patients with affective illness, ovulatory disturbances may be the presenting symptom. Thorough psychosocial evaluation may be an important tool in the diagnosis of and therapy for anovulation.
抑郁症与生长激素、催乳素及促肾上腺皮质激素 - 皮质醇的垂体反应可逆性异常有关。我们在一名假孕患者中观察到了类似的神经内分泌异常。随着假孕症状的缓解，激素反应恢复正常。卵巢对人绒毛膜促性腺激素（HCG）的反应表明，假孕与多囊卵巢疾病类似，起源于下丘脑 - 垂体中枢，神经内分泌数据与可逆性抑郁相符。在情感性疾病患者中，排卵障碍可能是首发症状。全面的社会心理评估可能是无排卵诊断和治疗的重要工具。
