Starkman M N, Marshall J C, La Ferla J, Kelch R P
Psychosom Med. 1985 Jan-Feb;47(1):46-57. doi: 10.1097/00006842-198501000-00005.
There is a paucity of information concerning the interrelationship of psychiatric and neuroendocrine abnormalities in pseudocyesis. We have studied two patients using a multimodal investigatory approach, with particular attention to the association of depression and alterations in endocrine secretory patterns. Both patients had abnormal growth hormone secretory patterns, as demonstrated by lack of sleep-associated peaks and the absence of a response to L-dopa administration. Both patients had elevated testosterone and estradiol levels and normal prolactin levels. Only the patient who met DSM III criteria for a major depressive episode had abnormally elevated luteinizing hormone (LH) levels and large LH pulse amplitudes. These findings, together with a review of cases reported in the literature, suggest that no single neuroendocrine profile is common to all patients with pseudocyesis.
关于假孕中精神异常与神经内分泌异常之间的相互关系，目前信息匮乏。我们采用多模式调查方法对两名患者进行了研究，特别关注抑郁与内分泌分泌模式改变之间的关联。两名患者的生长激素分泌模式均异常，表现为缺乏与睡眠相关的峰值以及对左旋多巴给药无反应。两名患者的睾酮和雌二醇水平升高，催乳素水平正常。只有符合DSM-III重性抑郁发作标准的患者促黄体生成素（LH）水平异常升高且LH脉冲幅度较大。这些发现，连同对文献报道病例的回顾，表明并非所有假孕患者都有单一的神经内分泌特征。
