Birky C W, Skavaril R V
J Theor Biol. 1984 Feb 21;106(4):441-7. doi: 10.1016/0022-5193(84)90001-8.
When a cell divides, some cytoplasmic organelles may be partitioned randomly between the daughters. The number of organelles in each daughter is usually calculated from the binomial distribution, which assumes that the organelles occupy zero volume. We developed equations to predict numerical partitioning taking the volume of the organelles and of the cell into account. The effect of large organelle volume is that daughter cells receive equal or nearly equal numbers of organelles more often than predicted by the binomial distribution. However, numerical solutions show that volume effects are very small unless the number of organelles is very small or they occupy more than about 50% of the available cell volume.
当细胞分裂时，一些细胞质细胞器可能会在子细胞之间随机分配。每个子细胞中细胞器的数量通常根据二项分布来计算，该分布假定细胞器占据的体积为零。我们开发了一些方程来预测考虑到细胞器和细胞体积的数值分配情况。大体积细胞器的影响是，子细胞接收相等或几乎相等数量细胞器的情况比二项分布预测的更为常见。然而，数值解表明，除非细胞器数量非常少或者它们占据了可用细胞体积的约50%以上，否则体积效应非常小。
