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慢性镁缺乏与应激状态下大鼠心脏的电解质和胶原蛋白含量(作者译)

[Electrolyte and collagen content of rat heart in chronic Mg-deficiency and stress (author's transl)].

作者信息

Günther T, Ising H, Merker H J

出版信息

J Clin Chem Clin Biochem. 1978 May;16(5):293-7.

PMID:670896
Abstract

In chronic Mg-deficiency, there is a decrease in the content of Mg and K+ in the heart muscle. The contents of Ca, Na+ and hydroxyproline increase. There is also an increased urinary excretion of adrenaline and especially noradrenaline. With simultaneous noise stress, these changes are even greater. The magnitude of the changes increases with the degree of Mg-deficiency. The changes in the contents of Na+, K+, Ca, Mg and hydroxyproline correlate with the excretion of noradrenaline. The increase in the collagen content can be verified by electron microscopy, and it is due to a stimulation of the fibrocytes.

摘要

在慢性镁缺乏时,心肌中镁和钾离子的含量会降低。钙、钠离子和羟脯氨酸的含量增加。肾上腺素尤其是去甲肾上腺素的尿排泄量也会增加。同时受到噪声应激时,这些变化会更加明显。变化的幅度随着镁缺乏程度的增加而增大。钠离子、钾离子、钙、镁和羟脯氨酸含量的变化与去甲肾上腺素的排泄相关。胶原蛋白含量的增加可通过电子显微镜证实,这是由于纤维细胞受到刺激所致。

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