Krawczuk J, Sawicki Z, Krawczyński J
J Clin Chem Clin Biochem. 1978 Jun;16(6):343-7. doi: 10.1515/cclm.1978.16.6.343.
The activity of lysozyme in feces was estimated in a control group of 50 healthy infants and in a group of 152 infants with acute diarrhoea. All infants investigated were artificially nourished. In the latter group the activity of lysozyme was estimated twice: a) at the beginning of clinically active phase of the disease and (b) in the convalescence period immediately after withdrawal of clinical symptoms. The range of normal values was 14.9--77.0 (average 44.0) of egg-white lysozyme units/g dry feces. In acute diarrhoea the activity of lysozyme in feces was found to be elevated in 72.4% of cases in the first determinations and in an additional 7.6% of cases in the second determination (i.e. a total of 80% of cases in both determinations). The average elevations of lysozyme activity in the feces and the dynamics of their normalization after withdrawal of clinical symptoms were generally related to the severity of the disease.
在50名健康婴儿组成的对照组以及152名患有急性腹泻的婴儿组中，对粪便中的溶菌酶活性进行了评估。所有接受调查的婴儿均为人工喂养。在后一组中，溶菌酶活性进行了两次评估：a）在疾病临床活跃期开始时；b）在临床症状消失后的恢复期。正常值范围为每克干粪便中蛋清溶菌酶单位14.9 - 77.0（平均44.0）。在急性腹泻中，首次测定时粪便中溶菌酶活性在72.4%的病例中升高，第二次测定时在另外7.6%的病例中升高（即两次测定总共80%的病例）。粪便中溶菌酶活性的平均升高以及临床症状消失后其恢复正常的动态变化通常与疾病的严重程度相关。
