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[动物接受亚致死剂量γ射线照射后胸腺DNA嘧啶区的即时变化]

[Changes in the pyrimidine blocks of thymic DNA immediately after gamma irradiation of the animal in a sublethal dosage].

作者信息

Vetchinkina A A, Kritskiĭ G A

出版信息

Radiobiologiia. 1984 Jan-Feb;24(1):63-6.

PMID:6709844
Abstract

Pyrimidine clusters of thymus DNA were determined in normal conditions and 5-10 min after gamma-irradiation of rabbits with a dose of 2 Gy. It was shown that a relative content of isopliths I and II significantly increased and that of isopliths V and VIII decreased in the exposed DNA as compared to normal. When isopliths were divided into the components a relative content of C2T2 fragments significantly increased in the exposed DNA while that of CT3 and T5 decreased.

摘要

在正常条件下以及用2戈瑞剂量的γ射线照射兔子后5 - 10分钟,测定了胸腺DNA的嘧啶簇。结果表明,与正常情况相比,受照射DNA中同片层体I和II的相对含量显著增加,而同片层体V和VIII的相对含量降低。当将同片层体分为各组分时,受照射DNA中C2T2片段的相对含量显著增加,而CT3和T5的相对含量降低。

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