Hernández J, Artillo S, Serrano M I, Serrano J S
Res Commun Chem Pathol Pharmacol. 1984 Feb;43(2):343-6.
The potential antidysrrhythmic effect of taurine has been studied both "in vitro" and "in vivo". "In vitro experiments were performed on a model of automaticity induced in the isolated right ventricle of the rat. The "in vivo" studies have been done on anesthetized rats, assessing the effect of taurine on the electrical activity of the heart by continuous ECG records. Taurine decreases the "in vitro" automatic ventricular frequency. "In vivo" reduces heart rate (P-P interval increases) and conduction through the ventricular myocardium (prolongs QRS interval duration). We conclude that taurine possesses experimentally antidysrrhythmic activity "in vitro" and "in vivo", that would warrant further research.
牛磺酸的潜在抗心律失常作用已在“体外”和“体内”进行了研究。“体外实验”是在大鼠离体右心室诱导的自律性模型上进行的。“体内研究”是在麻醉大鼠身上进行的，通过连续心电图记录评估牛磺酸对心脏电活动的影响。牛磺酸降低“体外”心室自动频率。“体内”降低心率（P-P间期增加）并减慢通过心室心肌的传导（延长QRS间期持续时间）。我们得出结论，牛磺酸在“体外”和“体内”均具有实验性抗心律失常活性，这值得进一步研究。
