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兔非髓鞘迷走神经肺受体及其对呼吸的反射作用

Non-myelinated vagal lung receptors and their reflex effects on respiration in rabbits.

作者信息

Trenchard D, Russell N J, Raybould H E

出版信息

Respir Physiol. 1984 Jan;55(1):63-79. doi: 10.1016/0034-5687(84)90117-8.

DOI:10.1016/0034-5687(84)90117-8
PMID:6709984
Abstract

The response characteristics of non-myelinated vagal lung receptors have been studied in the anaesthetized rabbit. The results indicate that the behaviour of these endings strongly resembles those found in cats and dogs and that they can be classified into 'pulmonary' 'bronchial' and 'pulmonary-bronchial' groups depending on their accessibility from either circulation. Experiments involving pericardial block with local anaesthetic to exclude responses from cardiac receptors and the use of sodium dithionite as a novel stimulus to 'pulmonary' endings alone, have shown that the predominant effect of these endings in the anaesthetized rabbit is to increase respiratory frequency. Reflex responses from 'bronchial' endings similar provided sufficient amount of the activating chemical was given.

摘要

在麻醉兔身上研究了无髓迷走神经肺感受器的反应特性。结果表明,这些末梢的行为与猫和狗身上发现的末梢非常相似,并且根据它们从循环中获取的途径,可分为“肺”“支气管”和“肺-支气管”组。涉及用局部麻醉剂进行心包阻滞以排除心脏感受器反应以及单独使用连二亚硫酸钠作为“肺”末梢的新型刺激物的实验表明,这些末梢在麻醉兔身上的主要作用是增加呼吸频率。如果给予足够量的激活化学物质,来自“支气管”末梢的类似反射反应也会出现。

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Non-myelinated vagal lung receptors and their reflex effects on respiration in rabbits.兔非髓鞘迷走神经肺受体及其对呼吸的反射作用
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