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Capability of tubulin and microtubules to incorporate and to release tyrosine and phenylalanine and the effect of the incorporation of these amino acids on tubulin assembly.

作者信息

Arce C A, Hallak M E, Rodriguez J A, Barra H S, Caputto R

出版信息

J Neurochem. 1978 Jul;31(1):205-10. doi: 10.1111/j.1471-4159.1978.tb12449.x.

DOI:10.1111/j.1471-4159.1978.tb12449.x
PMID:671018
Abstract
摘要

相似文献

1
Capability of tubulin and microtubules to incorporate and to release tyrosine and phenylalanine and the effect of the incorporation of these amino acids on tubulin assembly.微管蛋白和微管结合与释放酪氨酸和苯丙氨酸的能力以及这些氨基酸的掺入对微管蛋白组装的影响。
J Neurochem. 1978 Jul;31(1):205-10. doi: 10.1111/j.1471-4159.1978.tb12449.x.
2
Release of C-terminal tyrosine from tubulin and microtubules at steady state.在稳态下从微管蛋白和微管中释放C末端酪氨酸。
Biochem J. 1985 Feb 15;226(1):311-7. doi: 10.1042/bj2260311.
3
Tyrosination of microtubules and non-assembled tubulin in brain slices.脑切片中微管和未组装微管蛋白的酪氨酸化
Eur J Biochem. 1987 Jan 2;162(1):137-41. doi: 10.1111/j.1432-1033.1987.tb10553.x.
4
Experimental phenylketonuria: replacement of carboxyl terminal tyrosine by phenylalanine in infant rat brain tubulin.实验性苯丙酮尿症:幼鼠脑微管蛋白中苯丙氨酸取代羧基末端酪氨酸。
Science. 1979 Oct 26;206(4417):463-5. doi: 10.1126/science.574315.
5
Incorporation of 3-nitrotyrosine into the C-terminus of alpha-tubulin is reversible and not detrimental to dividing cells.3-硝基酪氨酸掺入α-微管蛋白的C末端是可逆的,且对分裂细胞无害。
Eur J Biochem. 2002 Oct;269(20):5037-45. doi: 10.1046/j.1432-1033.2002.03220.x.
6
Release of [14C]tyrosine from tubulinyl-[14C]tyrosine by brain extract. Separation of a carboxypeptidase from tubulin-tyrosine ligase.脑提取物从微管蛋白基-[14C]酪氨酸中释放[14C]酪氨酸。从微管蛋白-酪氨酸连接酶中分离出一种羧肽酶。
Mol Cell Biochem. 1978 Feb 24;19(1):17-21. doi: 10.1007/BF00231230.
7
Total tubulin and its aminoacylated and non-aminoacylated forms during the development of rat brain.大鼠脑发育过程中的总微管蛋白及其氨酰化和非氨酰化形式。
Eur J Biochem. 1980 Aug;109(2):439-46. doi: 10.1111/j.1432-1033.1980.tb04813.x.
8
Incorporation of L-tyrosine, L-phenylalanine and L-3,4-dihydroxyphenylalanine as single units into rat brain tubulin.
Eur J Biochem. 1975 Nov 1;59(1):145-9. doi: 10.1111/j.1432-1033.1975.tb02435.x.
9
On the mechanism of turnover of the carboxy-terminal tyrosine of the alpha chain of tubulin.关于微管蛋白α链羧基末端酪氨酸周转的机制
Eur J Biochem. 1980 Aug;109(1):207-16. doi: 10.1111/j.1432-1033.1980.tb04786.x.
10
Enzymatic detyrosination of tubulin tyrosinated in rat brain slices and extracts.大鼠脑切片和提取物中酪氨酸化微管蛋白的酶促去酪氨酸化作用。
J Neurochem. 1982 Jan;38(1):112-5. doi: 10.1111/j.1471-4159.1982.tb10860.x.

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L-Dopa-modified microtubules lead to synapse instability in cultured neurons: possible implications in Parkinson's disease therapy.左旋多巴修饰的微管导致培养神经元中的突触不稳定:对帕金森病治疗的潜在影响。
NPJ Parkinsons Dis. 2025 Oct 17;11(1):298. doi: 10.1038/s41531-025-01143-4.
2
Tubulin post-translational modifications control neuronal development and functions.微管蛋白翻译后修饰调控神经元的发育和功能。
Dev Neurobiol. 2021 Apr;81(3):253-272. doi: 10.1002/dneu.22774. Epub 2020 Aug 29.
3
Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
血管抑肽介导的去酪氨酸化的分子基础及其对纺锤体功能和有丝分裂的影响。
Cell Res. 2019 Jul;29(7):533-547. doi: 10.1038/s41422-019-0187-y. Epub 2019 Jun 6.
4
Post-Translational Incorporation of L-Phenylalanine into the C-Terminus of α-Tubulin as a Possible Cause of Neuronal Dysfunction.L-苯丙氨酸在α-微管蛋白 C 末端的翻译后掺入可能是神经元功能障碍的原因。
Sci Rep. 2016 Dec 1;6:38140. doi: 10.1038/srep38140.
5
Bisphosphorylated PEA-15 sensitizes ovarian cancer cells to paclitaxel by impairing the microtubule-destabilizing effect of SCLIP.双膦酸盐化 PEA-15 通过损害 SCLIP 的微管去稳定化作用使卵巢癌细胞对紫杉醇敏感。
Mol Cancer Ther. 2013 Jun;12(6):1099-111. doi: 10.1158/1535-7163.MCT-12-0737. Epub 2013 Mar 29.
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Post-translational incorporation of the antiproliferative agent azatyrosine into the C-terminus of alpha-tubulin.抗增殖剂氮杂酪氨酸在翻译后掺入α-微管蛋白的C末端。
Biochem J. 2003 Oct 1;375(Pt 1):121-9. doi: 10.1042/BJ20030776.
7
Cloning of rat olfactory bulb tubulin tyrosine ligase cDNA: a dominant negative mutant and an antisense cDNA increase the proliferation rate of cells in culture.大鼠嗅球微管蛋白酪氨酸连接酶cDNA的克隆:一种显性负性突变体和反义cDNA可提高培养细胞的增殖率。
Neurochem Res. 2002 Nov;27(11):1453-8. doi: 10.1023/a:1021640203644.
8
Structure-function relationships in yeast tubulins.酵母微管蛋白中的结构-功能关系。
Mol Biol Cell. 2000 May;11(5):1887-903. doi: 10.1091/mbc.11.5.1887.
9
Tubulin carboxypeptidase/microtubules association can be detected in the distal region of neural processes.
Neurochem Res. 2000 Jan;25(1):27-36. doi: 10.1023/a:1007579113813.
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The third tubulin pool.第三个微管蛋白库。
Neurochem Res. 2000 Jan;25(1):11-8. doi: 10.1023/a:1007575012904.