Poberezkina N B, Khmelevskiĭ Iu V
Ukr Biokhim Zh (1978). 1984 Jan-Feb;56(1):75-8.
It is found that glutathione reductase and superoxidismutase activity decreases in postmitochondrial fraction of the myocardium tissue under cardiovascular insufficiency of the hemodynamic type. In erythrocytes the activity of lipoperoxide-detoxicating glutathione peroxidase--GSH-peroxidase II lowers and that of hydrogen peroxide-utilizing GSH-peroxidase I grows. Disturbances in the antioxidant enzymic systems are discussed for their role in development of cardiac insufficiency.
发现在血液动力学型心血管功能不全时，心肌组织线粒体后部分中的谷胱甘肽还原酶和超氧化物歧化酶活性降低。在红细胞中，脂质过氧化物解毒的谷胱甘肽过氧化物酶（谷胱甘肽过氧化物酶II）活性降低，而利用过氧化氢的谷胱甘肽过氧化物酶I活性升高。讨论了抗氧化酶系统的紊乱在心脏功能不全发展中的作用。
