Dzhandzhgava T G, Shakarishvili R R
Vopr Med Khim. 1991 Sep-Oct;37(5):79-82.
Antioxidant drugs: alpha-tocopherol acetate and "Selenium" (Finland) were used in treatment of patients with small ischemic insult and middle severity ischemic insult; the state of endogenous antioxidant system and intensity of lipid peroxidation were studied in erythrocytes within various periods of diseases. Content of diene conjugates and malonic dialdehyde was decreased, while activity of superoxide dismutase, catalase, glutathione peroxidase and reductase was increased after administration of both these antioxidants during treatment of the brain circulation impairments. Simultaneous use of the drugs caused the highest effect which occurred due to their influence on various pathways of the endogenous antioxidant system.
α-生育酚醋酸酯和“硒”（芬兰产）用于治疗轻度缺血性损伤和中度缺血性损伤患者；在疾病的不同阶段研究了红细胞内源性抗氧化系统的状态和脂质过氧化强度。在治疗脑循环障碍期间，使用这两种抗氧化剂后，二烯共轭物和丙二醛的含量降低，而超氧化物歧化酶、过氧化氢酶、谷胱甘肽过氧化物酶和还原酶的活性增加。同时使用这些药物产生的效果最佳，这是由于它们对内源性抗氧化系统的各种途径产生了影响。
