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伴有精神症状和共济失调的慢性脑干脑炎：三例尸检报告

Chronic brainstem encephalitis with mental symptoms and ataxia: report of three cases with necropsy.

作者信息

Ueno T, Takahata N

出版信息

J Neurol Neurosurg Psychiatry. 1978 Jun;41(6):516-24. doi: 10.1136/jnnp.41.6.516.

DOI:10.1136/jnnp.41.6.516
PMID:671063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC493079/
Abstract

Three necropsied cases of chronic, sporadic brainstem encephalitis of unknown aetiology are presented. Since their outstanding symptoms were dementia and ataxia of a progressive nature, a noninflammatory disease of the central nervous system was suspected. Neuropathological studies showed chronic inflammatory changes mainly in the brainstem without the presence of inclusion bodies or viral particles. Compared to cases previously reported as brainstem encephalitis, the clinical and pathological findings observed in these cases have rather peculiar characteristics.

摘要

本文报告了3例病因不明的慢性散发性脑干脑炎尸检病例。由于其突出症状为进行性痴呆和共济失调，怀疑为中枢神经系统非炎性疾病。神经病理学研究显示，慢性炎症改变主要见于脑干，未见包涵体或病毒颗粒。与既往报道的脑干脑炎病例相比，这些病例的临床和病理表现具有相当独特的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/d3b75c43f325/jnnpsyc00144-0037-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/b892639b65a7/jnnpsyc00144-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/c649002cec87/jnnpsyc00144-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/6a525a159724/jnnpsyc00144-0037-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/d3b75c43f325/jnnpsyc00144-0037-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/b892639b65a7/jnnpsyc00144-0036-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/c649002cec87/jnnpsyc00144-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/6a525a159724/jnnpsyc00144-0037-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa47/493079/d3b75c43f325/jnnpsyc00144-0037-c.jpg

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Chronic brainstem encephalitis with mental symptoms and ataxia: report of three cases with necropsy.伴有精神症状和共济失调的慢性脑干脑炎：三例尸检报告
J Neurol Neurosurg Psychiatry. 1978 Jun;41(6):516-24. doi: 10.1136/jnnp.41.6.516.
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J Neurol Neurosurg Psychiatry. 1988 Aug;51(8):1084-7. doi: 10.1136/jnnp.51.8.1084.

本文引用的文献

1
Acute focal brain-stem lesions with favourable course. ("Brain stem encephalitis").病程良好的急性局灶性脑干病变。（“脑干脑炎”）
Acta Neurol Scand. 1961;37(4):297-316. doi: 10.1111/j.1600-0404.1961.tb01069.x.
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[A CASE OF THE ENCEPHALITIS LOCALIZED MAINLY IN THE BRAIN STEM WITH THE DEMYELINATION OF THE UNILATERAL CENTRUM SEMIOVALE].[1例主要位于脑干并伴有单侧半卵圆中心脱髓鞘的脑炎]
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Brain-stem encephalitis; further observations on a grave syndrome with benign prognosis.脑干脑炎；关于一种预后良好的严重综合征的进一步观察
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Brain-stem encephalitis and epidemic vertigo.脑干脑炎与流行性眩晕
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[Anatomo-clinical study of a case of encephalitis of the brain stem].[一例脑干脑炎病例的解剖临床研究]
Rev Neurol (Paris). 1967 Feb;116(2):141-60.
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Atypical encephalitis of the brain stem.脑干非典型性脑炎
Neuropatol Pol. 1966;4:Suppl:705-7.
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Encephalomyelitis with carcinoma.癌性脑脊髓炎
Brain. 1965 Sep;88(3):449-64. doi: 10.1093/brain/88.3.449.
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[An autopsy case of brain stem-encephalitis].[一例脑干脑炎尸检病例]
Seishin Shinkeigaku Zasshi. 1968 Jan;70(1):1-10.
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[Sporadic encephalitides].[散发性脑炎]
Arch Psychiatr Nervenkr (1970). 1969;212(2):200-6. doi: 10.1007/BF00342980.