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11例自杀病例中三环类抗抑郁药(TCA)母体药物的死后血药浓度。

Postmortem blood concentrations of parent tricyclic antidepressant (TCA) drugs in 11 cases of suicide.

作者信息

Hanzlick R L

出版信息

Am J Forensic Med Pathol. 1984 Mar;5(1):11-3. doi: 10.1097/00000433-198403000-00003.

DOI:10.1097/00000433-198403000-00003
PMID:6711512
Abstract

The blood levels of parent tricyclic antidepressant (TCA) drugs in 11 cases of suicide are reviewed. Values ranged from 0.11 mg% to 2.4 mg% with a mean of 0.80 mg%, which is consistant with the recent literature. The data suggest that in autopsy cases where TCA tissue levels or TCA metabolite concentrations could not be, or were not determined, blood levels of parent TCA drugs exceeding 0.1 mg% may be regarded confidently as the cause of death when no other cause is present.

摘要

回顾了11例自杀案例中三环类抗抑郁药(TCA)母体药物的血药浓度。浓度范围为0.11mg%至2.4mg%,平均为0.80mg%,这与最近的文献一致。数据表明,在尸检案例中,若无法或未测定TCA组织浓度或TCA代谢物浓度,当不存在其他死因时,母体TCA药物血药浓度超过0.1mg%可被确认为死因。

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