Pfenninger E, Kilian J
Anaesthesist. 1984 Feb;33(2):115-20.
13 cases of severe cerebral trauma were subjected to varying degrees of elevation of the upper trunk (0 degrees, 15 degrees, 30 degrees, 45 degrees) and to head-raising only (0 degrees, 15 degrees, 30 degrees). The intracranial pressure and mean arterial pressure were measured in these positions. On raising the upper half of the body by 15 degrees, intracranial pressure fell from a mean of 35.3 mm Hg to 28.7 mm Hg, and to 25.2 mm Hg on raising to 30 degrees. Further elevation to 45 degrees resulted in an increase in pressure. In contrast, the mean arterial pressure fell constantly as elevation increased, resulting in a decrease in cerebral perfusion pressure at levels above 30 degrees. In no cases did raising of the head alone result in a lowering of pressure. Instead, potentially dangerous increases were observed.
13例重度脑外伤患者接受了不同程度的上半身抬高（0度、15度、30度、45度）以及仅抬高头部（0度、15度、30度）的操作。在这些体位下测量颅内压和平均动脉压。将上半身抬高15度时，颅内压从平均35.3毫米汞柱降至28.7毫米汞柱，抬高至30度时降至25.2毫米汞柱。进一步抬高至45度则导致压力升高。相比之下，随着抬高程度增加，平均动脉压持续下降，导致在高于30度的水平时脑灌注压降低。单独抬高头部在任何情况下都不会导致压力降低。相反，观察到有潜在危险的压力升高。
