Gusovsky F, Sabelli H, Fawcett J, Edwards J, Javaid J I
Anal Biochem. 1984 Jan;136(1):202-7. doi: 10.1016/0003-2697(84)90326-9.
A gas-liquid chromatographic procedure to measure total phenylacetic acid in urine is described. The method is simple, rapid, and reliable. Normal subjects (N = 48) excreted 141.1 +/- 10.1 mg/24 h. Untreated depressed patients (N = 42) excreted 102.77 +/- 15.9 mg/24 h. The difference in the means is significant and supports the role of phenylacetic acid as a biological marker in certain kinds of mental illnesses.
本文描述了一种用于测量尿液中总苯乙酸的气-液色谱分析方法。该方法简单、快速且可靠。正常受试者（N = 48）每24小时排泄141.1±10.1毫克。未经治疗的抑郁症患者（N = 42）每24小时排泄102.77±15.9毫克。平均值的差异具有显著性，这支持了苯乙酸作为某些精神疾病生物标志物的作用。
