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非离子树脂柱液相色谱法测定复方片剂中的水杨酸和阿司匹林

Determination of salicylic acid and aspirin in multicomponent tablets by liquid chromatography on a nonionic resin.

作者信息

Baum R G, Cantwell F F

出版信息

J Pharm Sci. 1978 Aug;67(8):1066-9. doi: 10.1002/jps.2600670811.

DOI:10.1002/jps.2600670811
PMID:671238
Abstract

Aspirin and free salicylic acid were determined in combinations containing caffeine, phenacetin, salicylamide, and acetaminophen by liquid chromatography on poly(methyl methacrylate) resin. Precision and accuracy were +/- 2% for salicylic acid, the latter at levels corresponding to 0.02% of the aspirin content.

摘要

采用聚(甲基丙烯酸甲酯)树脂液相色谱法测定了含有咖啡因、非那西丁、水杨酰胺和对乙酰氨基酚的组合物中的阿司匹林和游离水杨酸。水杨酸的精密度和准确度为±2%,后者对应的水平为阿司匹林含量的0.02%。

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1
Determination of salicylic acid and aspirin in multicomponent tablets by liquid chromatography on a nonionic resin.非离子树脂柱液相色谱法测定复方片剂中的水杨酸和阿司匹林
J Pharm Sci. 1978 Aug;67(8):1066-9. doi: 10.1002/jps.2600670811.
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Direct spectrophotometric determination of salicylic acid, acetylsalicylic acid, salicylamide, caffeine, and phenacetin in tablets or powders.
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High-pressure liquid chromatographic analysis of paracetamol, caffeine and acetylsalicylic acid in tablets. Salicylic acid quantitation.片剂中对乙酰氨基酚、咖啡因和阿司匹林的高压液相色谱分析。水杨酸定量。
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Simultaneous determination of aspirin and salicylic acid in bulk aspirin and in plain, buffered, and enteric-coated tablets by high-pressure liquid chromatography with UV and fluorescence detectors.采用配备紫外和荧光检测器的高压液相色谱法同时测定原料药阿司匹林以及普通片剂、缓冲片剂和肠溶衣片中的阿司匹林和水杨酸。
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