Delans R J, Biuso J D, Saba S R, Ramirez G
Arch Intern Med. 1984 May;144(5):1074-6.
Campylobacter fetus subspecies jejuni is a recognized pathogen of the gastrointestinal (GI) tract resulting in a spectrum of illness from mild gastroenteritis to severe colitis with bloody diarrhea. Campylobacter is also being recognized as capable of producing systemic illness. Furthermore, antibody response, hypocomplementemia, and bacteremia with enterotoxic organisms have been described. Many of the clinical features, both local (le, in the GI tract) and systemic, parallel those of Shigella. Since the hemolytic uremic syndrome (HUS) may be produced by the effect of endotoxins or the immunocomplex on vascular endothelium in susceptible patients, it is expected that this syndrome may follow Campylobacter enteritis as it does Shigella enteritis. We, therefore, believe Campylobacter jejuni enteritis should be considered as one of the causative agents capable of inducing the HUS.
空肠弯曲菌胎儿亚种是一种公认的胃肠道病原体，可导致从轻度肠胃炎到伴有血性腹泻的严重结肠炎等一系列疾病。弯曲菌也被认为能够引发全身性疾病。此外，还描述了抗体反应、补体减少症以及肠毒素性生物体导致的菌血症。许多局部（即胃肠道）和全身性的临床特征与志贺氏菌相似。由于溶血尿毒综合征（HUS）可能是由内毒素或免疫复合物对易感患者血管内皮的作用产生的，因此预计这种综合征可能像志贺氏菌肠炎一样继发于弯曲菌肠炎。所以，我们认为空肠弯曲菌肠炎应被视为能够诱发溶血尿毒综合征的病原体之一。
