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微波辐射诱导培养的人神经母细胞瘤细胞中钙离子外流。

Microwave radiation-induced calcium ion efflux from human neuroblastoma cells in culture.

作者信息

Dutta S K, Subramoniam A, Ghosh B, Parshad R

出版信息

Bioelectromagnetics. 1984;5(1):71-8. doi: 10.1002/bem.2250050108.

DOI:10.1002/bem.2250050108
PMID:6712751
Abstract

Monolayer cultures of human neuroblastoma cells were exposed to 915-MHz radiation, with or without sinusoidal amplitude modulation (80%) at 16 Hz, at specific absorption rates (SAR) for the culture medium and cells of 0.00, 0.01, 0.05, 0.075, 0.1, 0.5, 0.75, 1.0, 1.5, 2, or 5 mW/g. A significant increase in the efflux of calcium ions (45Ca2+) as compared to unexposed control cultures occurred at two SAR values: 0.05 and 1 mW/g. Increased efflux at 0.05 mW/g was dependent on the presence of amplitude modulation at 16 Hz but at the higher value it was not. These results indicate that human neuroblastoma cells are sensitive to extremely low levels of microwave radiation at certain narrow ranges of SAR.

摘要

将人神经母细胞瘤细胞的单层培养物暴露于915兆赫的辐射下,该辐射有或没有16赫兹的正弦幅度调制(80%),培养基和细胞的比吸收率(SAR)分别为0.00、0.01、0.05、0.075、0.1、0.5、0.75、1.0、1.5、2或5毫瓦/克。与未暴露的对照培养物相比,在两个比吸收率值(0.05和1毫瓦/克)下,钙离子(45Ca2+)外流显著增加。在0.05毫瓦/克时外流增加取决于16赫兹的幅度调制的存在,但在较高值时则不然。这些结果表明,在特定狭窄的比吸收率范围内,人神经母细胞瘤细胞对极低水平的微波辐射敏感。

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