• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Experimental model of proliferative vitreoretinopathy (PVR) in the vitrectomised eye: effect of silicone oil.

作者信息

Lean J S, van der Zee W A, Ryan S J

出版信息

Br J Ophthalmol. 1984 May;68(5):332-5. doi: 10.1136/bjo.68.5.332.

DOI:10.1136/bjo.68.5.332
PMID:6712912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040334/
Abstract

Silicone oil alone or as an adjunct to vitrectomy is widely used for the treatment of retinal detachment complicated by proliferative vitreoretinopathy (PVR). It appears to reduce the tendency for recurrent traction detachment, but the mechanism of this action is obscure. We have studied the effects of silicone oil in an experimental animal model. Twenty five thousand homologous fibroblasts were injected into the aphakic vitrectomised rabbit eye, and traction detachment of the vascularised retina (medullary rays) regularly resulted. Intraocular silicone oil did not influence the development of this experimental detachment.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85af/1040334/4c4027b6956e/brjopthal00149-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85af/1040334/4c4027b6956e/brjopthal00149-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85af/1040334/4c4027b6956e/brjopthal00149-0064-a.jpg

相似文献

1
Experimental model of proliferative vitreoretinopathy (PVR) in the vitrectomised eye: effect of silicone oil.
Br J Ophthalmol. 1984 May;68(5):332-5. doi: 10.1136/bjo.68.5.332.
2
Intraocular injection of silicone oil for experimental proliferative vitreoretinopathy.
Am J Ophthalmol. 1983 May;95(5):663-7. doi: 10.1016/0002-9394(83)90387-2.
3
Temporary use of silicone oil in the treatment of proliferative vitreoretinopathy. An experimental study with a new animal model.
Graefes Arch Clin Exp Ophthalmol. 1983;221(1):46-53. doi: 10.1007/BF02171731.
4
Silicone oil for retinal detachment with advanced proliferative vitreoretinopathy following failed vitrectomy for proliferative diabetic retinopathy.用于增殖性糖尿病视网膜病变玻璃体切割术失败后伴有晚期增殖性玻璃体视网膜病变的视网膜脱离的硅油
Am J Ophthalmol. 1986 Feb 15;101(2):181-6. doi: 10.1016/0002-9394(86)90591-x.
5
Retinoic acid in silicone and silicone-fluorosilicone copolymer oils in a rabbit model of proliferative vitreoretinopathy.在增生性玻璃体视网膜病变兔模型中，视黄酸存在于硅酮及硅酮 - 氟硅酮共聚物油中。
Invest Ophthalmol Vis Sci. 1995 Nov;36(12):2388-95.
6
The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy.在玻璃体视网膜病变晚期的视网膜脱离玻璃体切除失败后硅油的应用。
Graefes Arch Clin Exp Ophthalmol. 1986;224(1):38-9. doi: 10.1007/BF02144131.
7
Regular silicone and fluorosilicone oil in the prevention of retinal detachment caused by experimental proliferative vitreoretinopathy.
Int Ophthalmol. 1988 Jan;11(3):171-4. doi: 10.1007/BF00130619.
8
Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy.
Graefes Arch Clin Exp Ophthalmol. 1991;229(5):464-7. doi: 10.1007/BF00166311.
9
Silicone oil as a delivery vehicle for BCNU in rabbit proliferative vitreoretinopathy.
Retina. 1993;13(3):245-50. doi: 10.1097/00006982-199313030-00011.
10
Silicone oil in vitreoretinal surgery. Part 1: Surgical techniques.
Retina. 1985 Fall-Winter;5(4):189-97. doi: 10.1097/00006982-198500540-00001.

引用本文的文献

1
Connective tissue growth factor as a mediator of intraocular fibrosis.结缔组织生长因子作为眼内纤维化的介质
Invest Ophthalmol Vis Sci. 2008 Sep;49(9):4078-88. doi: 10.1167/iovs.07-1302. Epub 2008 Apr 30.
2
Proliferative vitreoretinopathy: pathobiology, surgical management, and adjunctive treatment.增殖性玻璃体视网膜病变：病理生物学、手术治疗及辅助治疗
Br J Ophthalmol. 1995 Oct;79(10):953-60. doi: 10.1136/bjo.79.10.953.
3
Regular silicone and fluorosilicone oil in the prevention of retinal detachment caused by experimental proliferative vitreoretinopathy.

本文引用的文献

1
A comparison of different cellular inocula in an experimental model of massive periretinal proliferation.
Am J Ophthalmol. 1982 May;93(5):559-64. doi: 10.1016/s0002-9394(14)77369-6.
2
Structural basis of contraction in vitreal fibrous membranes.玻璃体纤维膜收缩的结构基础。
Br J Ophthalmol. 1981 Nov;65(11):737-49. doi: 10.1136/bjo.65.11.737.
3
Epiretinal and vitreous membranes. Comparative study of 56 cases.视网膜前膜和玻璃体膜。56例的对比研究。
Arch Ophthalmol. 1981 Aug;99(8):1445-54. doi: 10.1001/archopht.1981.03930020319025.
Int Ophthalmol. 1988 Jan;11(3):171-4. doi: 10.1007/BF00130619.
4
Randomized clinical trial of intraocular silicone vs. gas in the management of complicated retinal detachment and vitreous hemorrhage.
Int Ophthalmol. 1987 Aug;10(4):221-34. doi: 10.1007/BF00155629.
5
Proliferative vitreoretinopathy--is it anything more than wound healing at the wrong place?增殖性玻璃体视网膜病变——它是否仅仅是在错误部位的伤口愈合？
Int Ophthalmol. 1990 Mar;14(2):105-17. doi: 10.1007/BF00154210.
4
Human massive periretinal proliferation. In vitro characteristics of cellular components.
Arch Ophthalmol. 1981 May;99(5):873-80. doi: 10.1001/archopht.1981.03930010873017.
5
Management of complex retinal detachments by vitrectomy and fluid/silicone exchange.通过玻璃体切除术及液体/硅油交换治疗复杂性视网膜脱离
Trans Ophthalmol Soc U K (1962). 1982 Apr;102 (Pt 1):203-5.
6
Intraocular injection of silicone oil for experimental proliferative vitreoretinopathy.
Am J Ophthalmol. 1983 May;95(5):663-7. doi: 10.1016/0002-9394(83)90387-2.
7
Pathology of vitreous membranes and the effect of haemorrhage and new vessels on the vitreous.
Trans Ophthalmol Soc U K (1962). 1975;95(3):382-6.
8
Geometry of intraocular gas used in retinal surgery.视网膜手术中使用的眼内气体的几何学
Mod Probl Ophthalmol. 1977;18:338-43.
9
Clinical-pathological correlation in massive periretinal proliferation.
Am J Ophthalmol. 1975 Nov;80(5):913-29. doi: 10.1016/0002-9394(75)90289-5.
10
Role of cell shape in growth control.细胞形状在生长控制中的作用。
Nature. 1978 Jun 1;273(5661):345-9. doi: 10.1038/273345a0.