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翼状胬肉与紫外线辐射：正相关。

Pterygium and ultraviolet radiation: a positive correlation.

作者信息

Moran D J, Hollows F C

出版信息

Br J Ophthalmol. 1984 May;68(5):343-6. doi: 10.1136/bjo.68.5.343.

DOI:10.1136/bjo.68.5.343
PMID:6712914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040336/
Abstract

Pterygium has long been believed to be an environmental disease, Ultraviolet (UV) radiation playing a major role in its development. In examination of more than 100 000 Aborigines and non-Aborigines in rural Australia a strong positive correlation between climatic UV radiation and pterygium prevalence was found, providing further evidence of a causal relationship. In addition interesting differences were found in prevalence in the different racial groups and between the sexes. These differences may be explained by differences in lifestyle.

摘要

长期以来，人们一直认为翼状胬肉是一种环境性疾病，紫外线（UV）辐射在其发病过程中起主要作用。在对澳大利亚农村地区10万多名原住民和非原住民进行检查时，发现气候紫外线辐射与翼状胬肉患病率之间存在很强的正相关性，这进一步证明了两者之间的因果关系。此外，还发现不同种族群体和不同性别之间在患病率上存在有趣的差异。这些差异可能由生活方式的不同来解释。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfa6/1040336/5d0aa8323a9d/brjopthal00149-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfa6/1040336/5d0aa8323a9d/brjopthal00149-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfa6/1040336/5d0aa8323a9d/brjopthal00149-0074-a.jpg

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本文引用的文献

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Climatic droplet keratopathy and pterygium.
Aust J Ophthalmol. 1981 Aug;9(3):199-206. doi: 10.1111/j.1442-9071.1981.tb01013.x.
2
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Lancet. 1981 Dec 5;2(8258):1249-50. doi: 10.1016/s0140-6736(81)91490-2.
组蛋白H3赖氨酸9三甲基化与翼状胬肉相关。
BMC Ophthalmol. 2025 Mar 3;25(1):106. doi: 10.1186/s12886-025-03939-7.
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The relationship between involutional ectropion and inflammatory disorders of the eyelids and ocular surface: insights from a large-scale national study.萎缩性睑外翻与眼睑及眼表炎性疾病之间的关系：一项全国性大规模研究的见解
Sci Rep. 2025 Feb 3;15(1):4059. doi: 10.1038/s41598-025-88138-6.
5
Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning.通过生物信息学和机器学习识别与翼状胬肉相关的生物标志物和免疫微环境。
Front Mol Biosci. 2024 Dec 11;11:1524517. doi: 10.3389/fmolb.2024.1524517. eCollection 2024.
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Key Clinical and Histopathological Features of a Pterygium-Like Induced Lesion in a Rabbit Model.兔模型中翼状胬肉样诱导病变的关键临床和组织病理学特征。
Transl Vis Sci Technol. 2024 Oct 1;13(10):1. doi: 10.1167/tvst.13.10.1.
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