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一项关于精神分裂症患者病前适应情况报告可靠性的研究。

A study of the reliability of reported premorbid adjustment in schizophrenic patients.

作者信息

Small N E, Mohs R C, Halperin R, Rosen W G, Masterson C, Kendler K S, Horvath T B, Davis K L

出版信息

Biol Psychiatry. 1984 Feb;19(2):203-11.

PMID:6713037
Abstract

A study was conducted to determine the interrater reliability and the inter-informant reliability of two rating scales commonly used with schizophrenic patients. Both scales were completed by two informants for each of 45 schizophrenics. The Levels of Functioning Scale, which measures current social functioning, gave consistent results both between raters and between informants. The Premorbid Asocial Adjustment Scale, which measures social functioning during childhood and adolescence, produced very high reliability between raters but very poor reliability between informants. This suggests that much of the data collected about premorbid adjustment of schizophrenic patients are not accurate and that attempts to correlate reported premorbid adjustment with biological measures may be invalid. Ways of increasing the reliability and validity of premorbid adjustment measures are discussed.

摘要

开展了一项研究,以确定常用于精神分裂症患者的两种评定量表的评定者间信度和信息提供者间信度。45名精神分裂症患者中的每一位都由两名信息提供者完成这两种量表的评定。用于测量当前社会功能的功能水平量表在评定者之间和信息提供者之间都给出了一致的结果。用于测量童年和青少年时期社会功能的病前社会适应量表在评定者之间具有很高的信度,但在信息提供者之间的信度非常差。这表明,收集到的关于精神分裂症患者病前适应情况的许多数据并不准确,而且试图将所报告的病前适应情况与生物学指标相关联的做法可能是无效的。文中讨论了提高病前适应测量的信度和效度的方法。

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引用本文的文献

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Evidence that transition from health to psychotic disorder can be traced to semi-ubiquitous environmental effects operating against background genetic risk.有证据表明,从健康到精神病障碍的转变可以追溯到普遍存在的环境影响对背景遗传风险的作用。
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Genetic Risk and Outcome of Psychosis (GROUP), a multi-site longitudinal cohort study focused on gene-environment interaction: objectives, sample characteristics, recruitment and assessment methods.遗传风险与精神病结局研究(GROUP):一项关注基因-环境交互作用的多中心纵向队列研究:目的、样本特征、招募和评估方法。
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