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23型肺炎链球菌荚膜多糖的结构

Structure of the capsular polysaccharide from Streptococcus pneumoniae type 23.

作者信息

Roy A, Roy N

出版信息

Carbohydr Res. 1984 Mar 15;126(2):271-7. doi: 10.1016/0008-6215(84)85384-7.

Abstract

The capsular polysaccharide from Streptococcus pneumoniae Type 23 (S-23) was found to contain D-galactose, D-glucose, L-rhamnose, glycerol, and phosphorus in the ratios of 1:1:2:0.6:1. Methylation analysis provided information about the linkages of the different sugar units. The sequence of the different sugar residues was confirmed by Smith degradation. Oxidation of S-23 with chromium trioxide indicated that all of the sugar units have the beta configuration. The results suggest the following structure for the repeating unit. (formula; see text)

摘要

发现来自23型肺炎链球菌(S-23)的荚膜多糖含有D-半乳糖、D-葡萄糖、L-鼠李糖、甘油和磷,其比例为1:1:2:0.6:1。甲基化分析提供了不同糖单元连接方式的信息。通过史密斯降解确定了不同糖残基的序列。用三氧化铬氧化S-23表明所有糖单元均具有β构型。结果表明重复单元具有以下结构。(分子式;见正文)

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