Lekakis J, Katsoyanni K, Trichopoulos D, Tsitouris G
Clin Cardiol. 1984 May;7(5):283-8. doi: 10.1002/clc.4960070506.
A prospective study of 208 consecutive survivors of acute myocardial infarction was undertaken to determine the differences between Q- and non-Q-wave infarction, concerning data from the history, clinical course, and 6-month follow-up. There were 177 patients with Q-wave infarction and 31 patients with non-Q-wave infarction. There were no significant differences for the following variables: age, sex, diabetes mellitus, smoking, positive family history, hypertension, obesity, previous infarction, history of unstable angina, heart failure or chronic obstructive pulmonary disease (COPD), Killip class in the Coronary Care Unit (CCU), arrhythmias and conduction defects in the CCU as well as drugs used. Patients with non-Q wave infarction had a higher incidence of stable angina before the myocardial infarction and a lower value of creatine kinase (CK) and serum glutamic oxalacetic transferase (SGOT). During the 6-month follow-up, 9 cardiac deaths and 17 reinfarctions occurred, while 74 patients presented angina. There were no differences between the two groups concerning the incidence of cardiac death or angina, but patients with non-Q-wave infarction had a higher incidence of reinfarction at 6 months (p less than 0.001). We conclude that although patients with non-Q-wave myocardial infarction have a lesser degree of myocardial damage, they have a high incidence of early reinfarction which puts them in a high-risk group.
对208例急性心肌梗死连续幸存者进行了一项前瞻性研究，以确定Q波梗死和非Q波梗死在病史、临床病程及6个月随访数据方面的差异。其中有177例Q波梗死患者和31例非Q波梗死患者。在以下变量方面无显著差异：年龄、性别、糖尿病、吸烟、阳性家族史、高血压、肥胖、既往梗死、不稳定型心绞痛病史、心力衰竭或慢性阻塞性肺疾病（COPD）、冠心病监护病房（CCU）的Killip分级、CCU中的心律失常和传导缺陷以及所用药物。非Q波梗死患者在心肌梗死前稳定型心绞痛的发生率较高，肌酸激酶（CK）和血清谷草转氨酶（SGOT）值较低。在6个月的随访期间，发生了9例心源性死亡和17例再梗死，同时有74例患者出现心绞痛。两组在心源性死亡或心绞痛的发生率方面无差异，但非Q波梗死患者在6个月时再梗死的发生率较高（p<0.001）。我们得出结论，尽管非Q波心肌梗死患者的心肌损伤程度较轻，但他们早期再梗死的发生率较高，这使他们处于高危组。
