Hazout S, Mignot J, Guiguet M, Valleron A J
Comput Biol Med. 1984;14(1):63-76. doi: 10.1016/0010-4825(84)90021-0.
In this study, we present a new method of the rectification of distorted chromosome image allowing a more accurate description of the chromosome by obtaining density profiles with a large choice of scan axes, and an automatic centromere localisation and determination of the centromeric index.
在本研究中,我们提出了一种矫正染色体畸变图像的新方法,通过获取大量扫描轴的密度分布图、自动定位着丝粒并确定着丝粒指数,能够更准确地描述染色体。