Mahler Y, Admoni M, Ticho U
Doc Ophthalmol. 1984 Feb 29;56(4):363-76. doi: 10.1007/BF00155681.
Anterior chamber constant rate perfusion studies were performed in normal living monkey eyes. On careful inspection, the IOP-flow relation was seen to consist of a three stage curve. In the low range of infusions (0-6 microliters/min) IOP raised linearly. In the middle range (6-12 microliters/min) it remained almost constant and raised, again with high infusion rates (12-25 microliters/min). Calculating outflow facility from this pressure-flow relationship, it was shown that C value was constant in the low infusion range, increased in the middle range and decreased slowly over the high infusion rate range. A comparison was made with a similar curve derived from flow of fluids through non completely collapsible tubes. The change of IOP following high infusion rates consisted of a decrease in the steady-state pressures achieved. Comparison with formerly observed close phenomena was made and some thoughts about possible causes were brought.
在正常活体猴眼中进行前房恒速灌注研究。经仔细观察，眼压-流量关系呈现为一条三段曲线。在低灌注范围（0 - 6微升/分钟），眼压呈线性升高。在中等范围（6 - 12微升/分钟），眼压几乎保持恒定，而在高灌注速率（12 - 25微升/分钟）时又会升高。根据这种压力-流量关系计算流出率，结果表明在低灌注范围内C值恒定，在中等范围内增加，在高灌注速率范围内缓慢下降。将其与通过非完全可塌陷管道的流体流动得出的类似曲线进行了比较。高灌注速率后眼压的变化包括达到的稳态压力降低。与先前观察到的类似现象进行了比较，并对可能的原因进行了一些思考。
