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促红细胞生成素、睾酮和甲状腺素对食鱼游蛇(Xenochrophis piscator)红细胞生成反应的影响

Erythropoietin, testosterone, and thyroxine in the erythropoietic response of the snake, Xenochrophis piscator.

作者信息

Pati A K, Thapliyal J P

出版信息

Gen Comp Endocrinol. 1984 Mar;53(3):370-4. doi: 10.1016/0016-6480(84)90264-8.

DOI:10.1016/0016-6480(84)90264-8
PMID:6714657
Abstract

The erythropoietic response of snakes was examined after injecting human urinary erythropoietin (Ep), testosterone propionate (TP), and L-thyroxine (T4), separately and in combinations, into starved ophids. The effect of starvation was reflected by a decrease in the number of erythrocytes, a fall in hemoglobin concentration, and a decline in hematocrit. Statistically significant elevation of erythrocyte number, hemoglobin concentration, and hematocrit was observed at 24 hr following the administration of Ep + T4, and Ep + TP + T4 into starved ophids. The erythrocyte number was also increased by T4 treatment at 24 hr. Furthermore, while T4 and Ep individually increased the red blood cell number at 168 hr, T4, TP + T4, and Ep + TP + T4 elevated the hemoglobin concentration and Ep + T4 and Ep + TP + T4 increased the hematocrit value. It is suggested that the influence of any one of the hormones utilized in the present study on blood morphology of fasted snakes depends to a greater extent on the presence or absence of the other hormone(s).

摘要

将人尿促红细胞生成素(Ep)、丙酸睾酮(TP)和L-甲状腺素(T4)分别及联合注射到饥饿的蛇类体内后,检测了蛇类的红细胞生成反应。饥饿的影响表现为红细胞数量减少、血红蛋白浓度下降和血细胞比容降低。在向饥饿的蛇类注射Ep + T4、Ep + TP + T4后24小时,观察到红细胞数量、血红蛋白浓度和血细胞比容有统计学意义的升高。T4处理在24小时时也使红细胞数量增加。此外,虽然T4和Ep单独在168小时时增加了红细胞数量,但T4、TP + T4和Ep + TP + T4提高了血红蛋白浓度,Ep + T4和Ep + TP + T4增加了血细胞比容值。提示本研究中使用的任何一种激素对禁食蛇类血液形态的影响在很大程度上取决于其他激素的存在与否。

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