Schramlová J, Blazek K
Folia Parasitol (Praha). 1984;31(1):37-44.
Histochemical studies on the cysticercus and surrounding tissue reaction were performed at various intervals after experimental infection. It was found that acid mucosubstances and proteins with SH- and SS-groups appeared first in the granulation tissue around the cysticercus (on about day 14 p.i.) and only later (on day 28 p.i.) in the tegument of the cysticercus where they were localized in the rim of microtriches. This envelope consisting of mucosubstances and proteins seems to be identical with the electron-dense substance found on the surface of developing cysticercus during electron-microscopical studies. It is considered to be a mimicry enabling the cysticerci to survive even in an immunologically unfavourable environment. Phospholipids were found in activated fibroblasts and in some cells of macrophage type on days 21 and 30 p.i. and in a large number in subtegumental cells of cysticercus on days 28-34 p.i. This phenomenon seems to be correlated with the increased activity of subtegumental cells of the larva in this period. In morphologically fully differentiated cysticerci, the reaction for phospholipids in subtegumental cells and distal cytoplasm was only feebly positive. Phospholipids were not detected in the rim of microtriches at any time after infection.
在实验感染后的不同时间间隔，对囊尾蚴及其周围组织反应进行了组织化学研究。结果发现，酸性粘多糖物质以及含有巯基和二硫键的蛋白质首先出现在囊尾蚴周围的肉芽组织中（感染后约14天），之后才出现在囊尾蚴的皮层中（感染后28天），它们定位于微毛的边缘。这种由粘多糖物质和蛋白质组成的包膜似乎与电子显微镜研究中在发育中的囊尾蚴表面发现的电子致密物质相同。它被认为是一种拟态，使囊尾蚴即使在免疫不利的环境中也能存活。在感染后21天和30天，在活化的成纤维细胞和一些巨噬细胞类型的细胞中发现了磷脂，在感染后28 - 34天，囊尾蚴的皮层下细胞中大量存在磷脂。这种现象似乎与幼虫在此期间皮层下细胞活性的增加有关。在形态学上完全分化的囊尾蚴中，皮层下细胞和远端细胞质中的磷脂反应仅呈弱阳性。感染后任何时候在微毛边缘均未检测到磷脂。
