霍乱毒素与膜神经节苷脂：正常细胞和转化细胞中的结合及腺苷酸环化酶激活 - Suppr

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Cholera toxin and membrane gangliosides: binding and adenylate cyclase activation in normal and transformed cells.

作者信息

O'Keefe E, Cuatecasas P

出版信息

J Membr Biol. 1978 Jul 21;42(1):61-79. doi: 10.1007/BF01870394.

DOI:10.1007/BF01870394

PMID:671528

Abstract

摘要

相似文献

Cholera toxin and membrane gangliosides: binding and adenylate cyclase activation in normal and transformed cells.霍乱毒素与膜神经节苷脂：正常细胞和转化细胞中的结合及腺苷酸环化酶激活

J Membr Biol. 1978 Jul 21;42(1):61-79. doi: 10.1007/BF01870394.

Role of membrane gangliosides in the binding and action of bacterial toxins.膜神经节苷脂在细菌毒素结合及作用中的作用。

J Membr Biol. 1982;69(2):85-97. doi: 10.1007/BF01872268.

Modification of ganglioside GM1. Effect of lipid moiety on choleragen action.神经节苷脂GM1的修饰。脂质部分对霍乱毒素作用的影响。

J Biol Chem. 1980 Aug 25;255(16):7657-64.

Adenylate cyclase in a fibroblast mutant defective in glycolipid and glycoprotein synthesis.在糖脂和糖蛋白合成存在缺陷的成纤维细胞突变体中的腺苷酸环化酶

Nature. 1978 Sep 21;275(5677):223-4. doi: 10.1038/275223a0.

Tryptophan residues of cholera toxin and its A and B protomers. Intrinsic fluorescence and solute quenching upon interacting with the ganglioside GM1, oligo-GM1, or dansylated oligo-GM1.霍乱毒素及其A和B亚基的色氨酸残基。与神经节苷脂GM1、寡聚GM1或丹磺酰化寡聚GM1相互作用时的固有荧光和溶质猝灭。

J Biol Chem. 1981 Jun 10;256(11):5489-96.

Cholera toxin.霍乱毒素

Biosci Rep. 1982 Mar;2(3):135-46. doi: 10.1007/BF01116376.

Cholera toxin and cell growth: role of membrane gangliosides.霍乱毒素与细胞生长：膜神经节苷脂的作用

Proc Natl Acad Sci U S A. 1974 Oct;71(10):4224-8. doi: 10.1073/pnas.71.10.4224.

Ultrastructural localization of cell membrane GM1 ganglioside by cholera toxin.利用霍乱毒素对细胞膜GM1神经节苷脂进行超微结构定位

Proc Natl Acad Sci U S A. 1977 Sep;74(9):3782-6. doi: 10.1073/pnas.74.9.3782.

Generation of cell surface neoganglioproteins. GM1-neoganglioproteins are non-functional receptors for cholera toxin.细胞表面新神经节苷脂蛋白的生成。GM1-新神经节苷脂蛋白是霍乱毒素的无功能受体。

J Biol Chem. 1990 May 5;265(13):7673-8.

Mechanism of action of cholera toxin: effect of receptor density and multivalent binding on activation of adenylate cyclase.霍乱毒素的作用机制：受体密度和多价结合对腺苷酸环化酶激活的影响。

J Membr Biol. 1980;54(1):51-60. doi: 10.1007/BF01875376.

引用本文的文献

Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes.淋巴细胞上荧光神经节苷脂重新分布和帽化的直接可视化。

J Cell Biol. 1984 Nov;99(5):1575-81. doi: 10.1083/jcb.99.5.1575.

Mechanism of action of choleragen and E. coli heat-labile enterotoxin: activation of adenylate cyclase by ADP-ribosylation.霍乱毒素和大肠杆菌不耐热肠毒素的作用机制：通过ADP-核糖基化激活腺苷酸环化酶。

Mol Cell Biochem. 1981 Jul 7;37(2):75-90. doi: 10.1007/BF02354931.

Mechanism of action of cholera toxin: studies on the lag period.霍乱毒素的作用机制：关于延迟期的研究

J Membr Biol. 1980;54(1):61-72. doi: 10.1007/BF01875377.

Membrane glycolipid and phospholipid composition of lipopolysaccharide-responsive and -nonresponsive murine B lymphocytes.脂多糖反应性和非反应性小鼠B淋巴细胞的膜糖脂和磷脂组成

Infect Immun. 1986 Jun;52(3):777-85. doi: 10.1128/iai.52.3.777-785.1986.

Calcitonin gene-related peptide stimulates proliferation of human endothelial cells.降钙素基因相关肽刺激人内皮细胞增殖。

Proc Natl Acad Sci U S A. 1990 May;87(9):3299-303. doi: 10.1073/pnas.87.9.3299.

Involvement of gangliosides in lymphocyte stimulation.神经节苷脂在淋巴细胞刺激中的作用。

Proc Natl Acad Sci U S A. 1979 Oct;76(10):5277-81. doi: 10.1073/pnas.76.10.5277.

本文引用的文献

Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。

J Biol Chem. 1951 Nov;193(1):265-75.

Preparation of iodine-131 labelled human growth hormone of high specific activity.高比活度碘-131标记人生长激素的制备

Nature. 1962 May 5;194:495-6. doi: 10.1038/194495a0.

METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS.分离脂肪细胞的代谢。I. 激素对葡萄糖代谢和脂肪分解的影响。

J Biol Chem. 1964 Feb;239:375-80.

Glycosphingolipids with Lewis blood group activity: uptake by human erythrocytes.具有Lewis血型活性的糖鞘脂：人红细胞的摄取

Science. 1969 May 2;164(3879):553-5. doi: 10.1126/science.164.3879.553.

Modified procedure for the synthesis of 32P-labelled ribonucleoside 5'-monophosphates of high specific activity.高比活度32P标记的核糖核苷5'-单磷酸的合成改进方法。

Biochim Biophys Acta. 1968 Feb 26;155(2):609-10. doi: 10.1016/0005-2787(68)90205-0.

Physical effects of tetanus toxin on model membranes containing ganglioside.破伤风毒素对含神经节苷脂的模型膜的物理效应。

J Mol Biol. 1972 Jun 14;67(1):49-57. doi: 10.1016/0022-2836(72)90385-3.

Chemical and physical properties of cholera exo-enterotoxin (choleragen) and its spontaneously formed toxoid (choleragenoid).霍乱外毒素（霍乱原）及其自发形成的类毒素（类霍乱原）的化学和物理性质。

Biochim Biophys Acta. 1972 Jan 26;257(1):158-66. doi: 10.1016/0005-2795(72)90265-6.

Incorporation of exogenous glycosphingolipids in plasma membranes of cultured hamster cells and concurrent change of growth behavior.

Biochem Biophys Res Commun. 1973 Oct 1;54(3):1039-45. doi: 10.1016/0006-291x(73)90798-5.

Affinity chromatography and structural analysis of Vibrio cholerae enterotoxin-ganglioside agarose and the biological effects of ganglioside-containing soluble polymers.霍乱弧菌肠毒素-神经节苷脂琼脂糖的亲和层析及结构分析与含神经节苷脂可溶性聚合物的生物学效应

Biochemistry. 1973 Oct 9;12(21):4253-64. doi: 10.1021/bi00745a033.

Vibrio cholerae choleragenoid. Mechanism of inhibition of cholera toxin action.霍乱弧菌类霍乱毒素。抑制霍乱毒素作用的机制。

Biochemistry. 1973 Aug 28;12(18):3577-81. doi: 10.1021/bi00742a034.

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