腺病毒12型基因401在转化感染中的功能。
Adenovirus type 12 gene 401 function in transforming infection.
作者信息
Ledinko N
出版信息
J Virol. 1978 Jun;26(3):828-31. doi: 10.1128/JVI.26.3.828-831.1978.
Abstract
The temperature-sensitive DNA-minus mutant, H12ts401, transformed two to eight times more hamster embryo cells than wild-type 12 adenovirus at 38.5 degrees C, but was unable to establish transformation of cultures of hamster embryo brain and rat 3Y1 cells at 41.5 and 40 degrees C, respectively. Another H12ts406 DNA-minus mutant was not defective in cell transformation at these restrictive temperatures. Both mutants, however, induced T-antigen and cell DNA synthesis after infection of 3Y1 cells at 40 degrees C.
摘要
温度敏感型DNA缺失突变体H12ts401在38.5摄氏度时转化仓鼠胚胎细胞的能力比野生型12型腺病毒高两到八倍，但在41.5摄氏度和40摄氏度时分别无法在仓鼠胚胎脑细胞培养物和大鼠3Y1细胞中建立转化。另一个H12ts406 DNA缺失突变体在这些限制温度下细胞转化方面没有缺陷。然而，这两种突变体在40摄氏度感染3Y1细胞后均诱导了T抗原和细胞DNA合成。
相似文献
1
Adenovirus type 12 gene 401 function in transforming infection.腺病毒12型基因401在转化感染中的功能。
J Virol. 1978 Jun;26(3):828-31. doi: 10.1128/JVI.26.3.828-831.1978.
2
Requirement of adenovirus type 12 gene 401 function for initiation of virus DNA synthesis.
J Gen Virol. 1979 Mar;42(3):651-4. doi: 10.1099/0022-1317-42-3-651.
3
Adenovirus type 12 gene 401 function and maintenance of transformation.腺病毒12型基因401的功能与转化维持
J Virol. 1979 Jan;29(1):250-60. doi: 10.1128/JVI.29.1.250-260.1979.
4
Abortive and transforming infection of rat cell line 3Y1 by adenovirus type 12.12型腺病毒对大鼠细胞系3Y1的顿挫感染和转化感染
J Virol. 1978 Mar;25(3):907-11. doi: 10.1128/JVI.25.3.907-911.1978.
5
Adenovirus type 12 gene 401 function and temperature sensitivity of cytochalasin B effects on transformed cells.
Intervirology. 1980;14(5-6):253-60. doi: 10.1159/000149194.
6
Transformation of rodent cells by DNA extracted from transformation-defective adenovirus mutants.用从转化缺陷型腺病毒突变体中提取的DNA对啮齿动物细胞进行转化。
J Virol. 1983 Jun;46(3):1039-44. doi: 10.1128/JVI.46.3.1039-1044.1983.
7
The adenovirus type 12 early-region 1B 58,000-Mr gene product is required for viral DNA synthesis and for initiation of cell transformation.腺病毒12型早期区域1B 58,000道尔顿基因产物是病毒DNA合成和细胞转化起始所必需的。
J Virol. 1986 Mar;57(3):792-801. doi: 10.1128/JVI.57.3.792-801.1986.
8
Low-level beta 1 protein kinase C expression in cloned rat embryo fibroblast cells enhances transformation induced by the adenovirus type 5 E1A gene.克隆大鼠胚胎成纤维细胞中低水平的β1蛋白激酶C表达增强了5型腺病毒E1A基因诱导的转化作用。
Mol Carcinog. 1991;4(4):328-37. doi: 10.1002/mc.2940040412.
9
Possible role of the 72,000 dalton DNA-binding protein in regulation of adenovirus type 5 early gene expression.72,000道尔顿DNA结合蛋白在调控5型腺病毒早期基因表达中的可能作用。
J Virol. 1978 Feb;25(2):664-74. doi: 10.1128/JVI.25.2.664-674.1978.
10
Synthesis of DNA, late polypeptides, and infectious virus by host-range mutants of adenovirus 5 in nonpermissive cells.腺病毒5型宿主范围突变体在非允许细胞中DNA、晚期多肽及传染性病毒的合成
Virology. 1978 Jun 15;87(2):463-7. doi: 10.1016/0042-6822(78)90148-4.
引用本文的文献
1
Adenovirus type 12 gene 401 function and maintenance of transformation.腺病毒12型基因401的功能与转化维持
J Virol. 1979 Jan;29(1):250-60. doi: 10.1128/JVI.29.1.250-260.1979.
本文引用的文献
1
Intravenous procaine (novocain).静脉注射普鲁卡因（奴佛卡因）。
Br Med J. 1947 Mar 15;1(4497):354. doi: 10.1136/bmj.1.4497.354-b.
2
IMMUNOFLUORESCENT STUDIES OF ADENOVIRUS 12 TUMORS AND OF CELLS TRANSFORMED OR INFECTED BY ADENOVIRUSES.腺病毒12肿瘤以及被腺病毒转化或感染的细胞的免疫荧光研究
J Exp Med. 1964 Oct 1;120(4):577-88. doi: 10.1084/jem.120.4.577.
3
Temperature-sensitive mutants of adenovirus type 12 defective in viral DNA synthesis.在病毒DNA合成方面存在缺陷的12型腺病毒温度敏感突变体。
J Virol. 1974 Sep;14(3):457-68. doi: 10.1128/JVI.14.3.457-468.1974.
4
5
Differential expression of transformation in rat and chicken cells infected with an avian sarcoma virus ts mutant.
Virology. 1973 Nov;56(1):369-74. doi: 10.1016/0042-6822(73)90314-0.
6
7
Genetic analysis of human adenovirus type 5 in permissive and nonpermissive cells.
Cold Spring Harb Symp Quant Biol. 1975;39 Pt 1:427-37. doi: 10.1101/sqb.1974.039.01.055.
8
Cell transformation: a study of regulation with types 5 and 12 adenovirus temperature-sensitive mutants.
Cold Spring Harb Symp Quant Biol. 1975;39 Pt 1:419-26. doi: 10.1101/sqb.1974.039.01.054.
9
Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovrius defective in viral DNA synthesis.来自感染了腺病毒温度敏感突变体的细胞的热不稳定DNA结合蛋白，该突变体在病毒DNA合成方面存在缺陷。
J Virol. 1975 Feb;15(2):348-54. doi: 10.1128/JVI.15.2.348-354.1975.
10
Persistence of type 5 adenovirus DNA in cells transformed by temperature-sensitive mutant, H5ts125.5型腺病毒DNA在温度敏感突变体H5ts125转化的细胞中的持久性。
Proc Natl Acad Sci U S A. 1977 Feb;74(2):785-8. doi: 10.1073/pnas.74.2.785.
Zotero 插件