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分娩过程中尿肾上腺素、去甲肾上腺素及血浆皮质醇浓度的变化

[Changes in urinary adrenaline and noradrenaline and plasma cortisol concentrations during labor and delivery].

作者信息

Yaginuma T, Okamura T, Miyata R, Takahashi M, Takeuchi T, Nishii O, Kobayashi T, Izumi R

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1984 Mar;36(3):354-8.

PMID:6715919
Abstract

Urinary adrenaline and noradrenaline concentrations were determined at 38-41 wks of gestation, admission for the onset of labor, 4 hrs after admission and at the cervical dilatation of 8-10 cm, immediately after delivery and on the next morning. Both catecholamine concentrations rose remarkably at the dilatation of 8-10 cm and were found to be still high immediately after delivery. The rise in adrenaline concentrations was much greater than noradrenaline. On the morning after delivery, the adrenaline concentrations fell significantly but noradrenaline remained high. The time-course of urinary catecholamines was similar to that of plasma reported by others. Serum cortisol concentrations rose significantly during labor and delivery but returned to the concentrations of 38-41 wks of gestation by the next morning. The present time course of adrenaline, noradrenaline and cortisol levels in urine or serum during labor, delivery and puerperium suggests that these hypersecretion may be due to emotional, physical and painful stress, respectively, considering literatures.

摘要

在妊娠38 - 41周、临产入院时、入院4小时后、宫颈扩张8 - 10厘米时、分娩后即刻及次日早晨测定尿中肾上腺素和去甲肾上腺素浓度。在宫颈扩张8 - 10厘米时,两种儿茶酚胺浓度均显著升高,且在分娩后即刻仍处于较高水平。肾上腺素浓度的升高幅度远大于去甲肾上腺素。在分娩后的早晨,肾上腺素浓度显著下降,但去甲肾上腺素仍处于较高水平。尿中儿茶酚胺的时间进程与其他人报道的血浆情况相似。血清皮质醇浓度在分娩过程中显著升高,但到次日早晨恢复到妊娠38 - 41周时的浓度。考虑到相关文献,目前产程、分娩及产褥期尿或血清中肾上腺素、去甲肾上腺素和皮质醇水平的时间进程表明,这些分泌过多可能分别归因于情绪、身体和疼痛应激。

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Nihon Sanka Fujinka Gakkai Zasshi. 1984 Mar;36(3):354-8.
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