Crassweller P O, Oreopoulos D G, Toguri A, Husdan H, Wilson D R, Rapoport A
J Urol. 1978 Jul;120(1):6-10. doi: 10.1016/s0022-5347(17)57021-4.
Studies have been done on patients with recurrent renal calculous disease, measuring in addition to the usual serum and urine constituents the inhibiting capacity of the urine and the activity products of calcium oxalate, octocalcium phosphate and brushite. Studies on the 24-hour urine calcium, phosphorus and uric acid and serum calcium indicate no essential differences between patients with calcium oxalate, mixed or uric acid stones and normal individuals. We were unable to demonstrate a difference in the inhibiting capacity of the urine between normal individuals and patients with calcium oxalate calculi, and levels of saturation of urine with calcium oxalate were identical in the calcium oxalate stone patients and normal individuals. The degree of saturation of urine with calcium phosphate is significantly greater in stone patients.
针对复发性肾石病患者开展了多项研究，除常规检测血清和尿液成分外，还测定了尿液的抑制能力以及草酸钙、磷酸八钙和透钙磷石的活性产物。对24小时尿钙、磷、尿酸及血清钙的研究表明，草酸钙结石、混合性结石或尿酸结石患者与正常个体之间并无本质差异。我们未能证实正常个体与草酸钙结石患者尿液抑制能力存在差异，且草酸钙结石患者与正常个体尿液中草酸钙的饱和度水平相同。结石患者尿液中磷酸钙的饱和度显著更高。
