镰状细胞病患儿的肺炎球菌败血症
Pneumococcal sepsis in children with sickle cell disease.
作者信息
Samuels-Reid J H
出版信息
J Natl Med Assoc. 1984 Mar;76(3):289-92.
Abstract
Pneumococcal sepsis has contributed to increased morbidity and mortality in patients with sickle cell disease. This case highlights the urgency of early diagnosis and the necessity of aggressive intervention in the management of sickle cell patients, particularly during the years of early childhood. It cannot be overemphasized that sickle cell patients, especially those less than 5 years of age, should be monitored carefully and institution of parenteral antibiotics should be undertaken early, even in those patients that present with mild symptoms.
摘要
肺炎球菌败血症导致镰状细胞病患者的发病率和死亡率上升。该病例凸显了早期诊断的紧迫性以及在镰状细胞病患者管理中积极干预的必要性，尤其是在幼儿期。必须着重强调的是，镰状细胞病患者，特别是那些年龄小于5岁的患者，应予以密切监测，即使是那些症状轻微的患者，也应尽早开始使用静脉抗生素治疗。
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引用本文的文献
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本文引用的文献
1
Pneumococcal septicemia in children with sickle cell anemia. Changing trend of survival.镰状细胞贫血患儿的肺炎球菌败血症。生存趋势的变化
JAMA. 1981 May 8;245(18):1839-42.
2
Functional asplenia in sickle-cell anemia.镰状细胞贫血中的功能性无脾症。
N Engl J Med. 1969 Oct 23;281(17):923-6. doi: 10.1056/NEJM196910232811703.
3
Bacterial infection and sickle cell anemia. An analysis of 250 infections in 166 patients and a review of the literature.细菌感染与镰状细胞贫血。对166例患者的250次感染进行分析并回顾文献。
Medicine (Baltimore). 1971 Mar;50(2):97-112.
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Deficiency of pneumococcal serum opsonizing activity in sickle-cell disease.镰状细胞病中肺炎球菌血清调理活性缺乏
N Engl J Med. 1968 Aug 29;279(9):459-66. doi: 10.1056/NEJM196808292790904.
5
An abnormality of the alternate pathway of complement activation in sickle-cell disease.镰状细胞病中补体激活替代途径的异常。
N Engl J Med. 1973 Apr 19;288(16):803-8. doi: 10.1056/NEJM197304192881601.
6
Bacterial meningitis and septicemia in sickle cell disease.镰状细胞病中的细菌性脑膜炎和败血症
Am J Dis Child. 1977 Jul;131(7):784-7. doi: 10.1001/archpedi.1977.02120200066014.
7
Failure of pneumococcal vaccine in children with sickle-cell disease.镰状细胞病患儿中肺炎球菌疫苗接种失败
N Engl J Med. 1979 Jul 5;301(1):26-7. doi: 10.1056/NEJM197907053010106.
8
Decreased opsonization for Streptococcus pneumoniae in sickle cell disease: studies on selected complement components and immunoglobulins.镰状细胞病中肺炎链球菌的调理作用降低：对选定补体成分和免疫球蛋白的研究。
J Pediatr. 1977 Sep;91(3):371-8. doi: 10.1016/s0022-3476(77)81303-6.
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