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核袋与核环的连续切片研究

A serial section study of nuclear pockets and loops.

作者信息

Senoo A, Fuse Y, Ghadially F N

出版信息

J Submicrosc Cytol. 1984 Apr;16(2):379-86.

PMID:6716536
Abstract

A serial section study of nuclear pockets in a lymphoma of the stomach showed that: 1) no tumour cell nucleus was free of pockets; 2) approximately 10 to 50 pockets occur on a nucleus; and 3) the pockets show a focal rather than a diffuse distribution on the nucleus. In most pockets cytoplasmic material is completely sequestrated and no channel of communication remains between the cytoplasm and the contents of the pocket. While most pockets contain cytoplasmic material, a few contain nuclear material. It would appear that these are two distinct and different lesions and that one does not evolve from the other. A serial section study of the so-called 'chromatin loops' shows that they are no more than fortuitous sections through pockets. The idea that 'chromatin loops' are cast off from the nucleus receives no support from our studies.

摘要

对胃淋巴瘤中核袋的连续切片研究表明

1)没有肿瘤细胞核不存在核袋;2)一个细胞核上大约出现10至50个核袋;3)核袋在细胞核上呈局灶性而非弥漫性分布。在大多数核袋中,细胞质物质被完全隔离,细胞质与核袋内容物之间不存在沟通通道。虽然大多数核袋含有细胞质物质,但少数含有核物质。看来这是两种不同且各异的病变,一种不会由另一种演变而来。对所谓“染色质环”的连续切片研究表明,它们不过是核袋的偶然切片。“染色质环”从细胞核脱落的观点未得到我们研究的支持。

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