Leary S L, Manning P J, Anderson L C
Lab Anim Sci. 1984 Feb;34(1):58-61.
Gastric foreign bodies were induced in laboratory rabbits by orogastric infusion of a liquid latex containing radiopaque dye which polymerizes in the acid environment within the stomach to form a solid mass. The rabbits were monitored clinically and radiographically for 6 months at which time gastrotomies were performed to remove the masses, followed by a 4-week observation period. None of the 14 rabbits became ill or anorectic during the 6-month period of clinical monitoring, and all gained weight. At gastrotomy, eight rabbits had both latex bezoars and trichobezoars . Though two rabbits died post-operatively from respiratory complications, the remaining 12 rabbits recovered without complications and regained their pre-operative body weight within 4 weeks. Five of 10 rabbits necropsied 1 month after gastrotomy had gastric trichobezoars . This led to a survey of the stomachs of 208 healthy slaughter-rabbits which revealed that 48 (23.1%) had trichobezoars weighing 1 to 24 g. The data suggested that gastric trichobezoars were common in rabbits and that few animals with these foreign bodies developed chronic anorexia. In addition, there appeared to be a high likelihood that trichobezoars recur in a high percentage of rabbits within several weeks postoperatively.
通过经口胃内注入含有不透射线染料的液体乳胶在实验兔中诱发胃内异物，该乳胶在胃内酸性环境中聚合形成固体团块。对这些兔子进行了6个月的临床和放射学监测，之后进行胃切开术以取出团块，随后进行为期4周的观察期。在6个月的临床监测期间，14只兔子均未生病或食欲不振，且全部体重增加。在胃切开术时，8只兔子既有乳胶毛粪石又有毛发粪石。尽管有2只兔子术后死于呼吸并发症，但其余12只兔子康复且无并发症，并在4周内恢复到术前体重。在胃切开术后1个月进行尸检的10只兔子中有5只存在胃毛发粪石。这促使对208只健康屠宰兔的胃进行调查，结果显示48只（23.1%）有重量为1至24克的毛发粪石。数据表明胃毛发粪石在兔子中很常见，且很少有患有这些异物的动物会出现慢性食欲不振。此外，术后几周内，相当比例的兔子似乎很有可能复发毛发粪石。
