Krugner-Higby L, Wolden-Hanson T, Gendron A, Atkinson R L
Research Animal Resources Center, University of Wisconsin at Madison, USA.
Lab Anim Sci. 1996 Dec;46(6):635-9.
Gastric trichobezoars (hair balls) are frequently found in rabbits but are rarely reported in rats. Several Wistar-Kyoto rats fed a semi-purified diet developed anorexia and abdominal tenderness. Proteolysis therapy with fresh papaya and commercially prepared enzyme was attempted in these rats but was not successful. The prevalence of trichobezoars at necropsy was 100%. We conclude that semi-purified diets contribute to trichobezoar formation in rats, but proteolysis therapy is not effective in dissolving the trichobezoars.
胃毛石（毛球）在兔子中很常见，但在大鼠中鲜有报道。几只喂食半纯化饮食的Wistar - Kyoto大鼠出现了厌食和腹部压痛症状。曾尝试用新鲜木瓜和市售酶对这些大鼠进行蛋白水解疗法，但未成功。尸检时毛石的发生率为100%。我们得出结论，半纯化饮食会促使大鼠形成毛石，但蛋白水解疗法对溶解毛石无效。
