Root I, Ohlson G B
J Anal Toxicol. 1984 Mar-Apr;8(2):91-4. doi: 10.1093/jat/8.2.91.
Two cases of overdose due to ingestion of trazodone are described. In one case, blood collected several hours following ingestion of an estimated 4 or more grams contained a trazodone concentration of 25.7 mg/L. Recovery was uneventful. The second case did not survive and death was attributed to the ingestion of multiple drugs in combination. Both cases were analyzed by high-pressure liquid chromatography and the methodology is given.
描述了两例因服用曲唑酮过量的病例。其中一例,在摄入估计4克或更多曲唑酮数小时后采集的血液中,曲唑酮浓度为25.7毫克/升。患者康复过程顺利。第二例患者未能存活,死亡归因于多种药物联合服用。两例均通过高压液相色谱法进行分析,并给出了分析方法。