Bell R D
Lymphology. 1984 Mar;17(1):10-4.
Several lines of research suggest that renal lymph is formed totally, or in part, as a filtrate of postglomerular blood. Even so, renal interstitial fluid dynamics is necessarily dominated by the rapid transfer of large volumes of reabsorbate from tubular lumen to peritubular capillary. To determine the effects of tubular reabsorption on lymph formation, renal lymph flow and composition were studied before and during alterations in tubular reabsorption produced by diuresis. A 25% reduction in whole kidney fluid reabsorption rate did not alter renal lymph flow or lymph protein concentration. A concomitant decrease in plasma protein concentration, however, suggests that any deficit in lymph flow resulting from decreased reabsorbate content may have been obscured by an increase in vascular filtration. An increase in renal lymph PAH and creatinine concentrations relative to those of arterial and renal venous blood plasma supports this conclusion. It appears that renal lymph flow may be determined by both vascular filtration and tubular reabsorption.
多项研究表明，肾淋巴液全部或部分是作为肾小球后血液的滤出液形成的。即便如此，肾间质液动力学必然主要由大量重吸收物质从肾小管腔快速转移至肾小管周围毛细血管所主导。为了确定肾小管重吸收对淋巴液形成的影响，在利尿导致肾小管重吸收改变之前及过程中，对肾淋巴液流量和成分进行了研究。全肾液体重吸收率降低25%并未改变肾淋巴液流量或淋巴液蛋白浓度。然而，血浆蛋白浓度同时降低，这表明重吸收物质含量减少导致的淋巴液流量任何不足可能已被血管滤过增加所掩盖。相对于动脉血和肾静脉血浆，肾淋巴液中对氨基马尿酸（PAH）和肌酐浓度升高支持了这一结论。看来肾淋巴液流量可能由血管滤过和肾小管重吸收共同决定。
