氯尼达明：培养的HeLa细胞及体内Meth-A肿瘤的热增敏剂。
Lonidamine: a hyperthermic sensitizer of HeLa cells in culture and of the Meth-A tumor in vivo.
作者信息
Kim J H, Kim S H, Alfieri A, Young C W, Silvestrini B
出版信息
Oncology. 1984;41 Suppl 1:30-5. doi: 10.1159/000225882.
PMID:6717892
Abstract
Lonidamine was studied in HeLa cell cultures and BALB/c mice with Meth-A fibrosarcoma. Lonidamine is a hyperthermia sensitizer, both in vivo and in vivo. In vitro the potentiating effects were higher at low pH conditions.
摘要
在HeLa细胞培养物以及患有Meth - A纤维肉瘤的BALB/c小鼠中对氯尼达明进行了研究。氯尼达明在体内和体外都是一种热疗增敏剂。在体外，低pH条件下其增效作用更高。
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