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氯尼达明：培养的HeLa细胞及体内Meth-A肿瘤的热增敏剂。

Lonidamine: a hyperthermic sensitizer of HeLa cells in culture and of the Meth-A tumor in vivo.

作者信息

Kim J H, Kim S H, Alfieri A, Young C W, Silvestrini B

出版信息

Oncology. 1984;41 Suppl 1:30-5. doi: 10.1159/000225882.

DOI:10.1159/000225882
PMID:6717892
Abstract

Lonidamine was studied in HeLa cell cultures and BALB/c mice with Meth-A fibrosarcoma. Lonidamine is a hyperthermia sensitizer, both in vivo and in vivo. In vitro the potentiating effects were higher at low pH conditions.

摘要

在HeLa细胞培养物以及患有Meth - A纤维肉瘤的BALB/c小鼠中对氯尼达明进行了研究。氯尼达明在体内和体外都是一种热疗增敏剂。在体外，低pH条件下其增效作用更高。

相似文献

1
Lonidamine: a hyperthermic sensitizer of HeLa cells in culture and of the Meth-A tumor in vivo.氯尼达明：培养的HeLa细胞及体内Meth-A肿瘤的热增敏剂。
Oncology. 1984;41 Suppl 1:30-5. doi: 10.1159/000225882.
2
Radiosensitization of Meth-A fibrosarcoma in mice by Lonidamine.氯尼达明对小鼠Meth-A纤维肉瘤的放射增敏作用
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Potentiation of radiation effects on multicellular tumor spheroids (MTS) of HeLa cells by lonidamine.
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Effects of lonidamine alone or combined with hyperthermia in some experimental cell and tumour systems.氯尼达明单独或与热疗联合在某些实验性细胞和肿瘤系统中的作用。
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Potentiation of radiation effects on two murine tumors by lonidamine.氯尼达明对两种小鼠肿瘤辐射效应的增强作用。
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Combination therapy: lonidamine, hyperthermia, and chemotherapy against the RIF-1 tumor in vivo.联合治疗：氯尼达明、热疗与化疗对体内RIF-1肿瘤的作用
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