Johnson L N, Krohel G B, Yeon E B, Parnes S M
Ophthalmology. 1984 Mar;91(3):209-17. doi: 10.1016/s0161-6420(84)34300-7.
Forty -seven of 79 patients with sinus and paranasal tumors had clinical, radiographic or operative evidence of orbital involvement. Seventy percent of those patients with orbital extension had clinical or radiographic involvement of the orbit at the time of initial presentation. Common presenting signs and symptoms included proptosis, nasal obstruction or discharge, nasal mass, facial and/or eye pain, visual loss, facial and/or lid edema and diplopia. The most common tumor seen was squamous cell carcinoma. The maxillary sinus was the most frequent site of origin. Three patients were misdiagnosed as having sinusitis on initial evaluation. A diagnosis of sinusitis is tentative and should be reevaluated early with repeat roentgenographic studies and biopsy, especially in the presence of protracted facial and eye pain. When ordering CT scans, one must specifically request cuts of the base of the sinuses and skull as routine brain CT scans do not evaluate those regions. Two of four patients with intractable pain unrelieved by narcotics obtained pain relief with cisplatinum.
79例鼻窦和鼻旁窦肿瘤患者中,47例有眼眶受累的临床、影像学或手术证据。眼眶扩展的患者中,70%在初次就诊时眼眶有临床或影像学受累表现。常见的症状和体征包括眼球突出、鼻塞或流涕、鼻肿物、面部和/或眼部疼痛、视力丧失、面部和/或眼睑水肿及复视。最常见的肿瘤是鳞状细胞癌。上颌窦是最常见的起源部位。3例患者初次评估时被误诊为鼻窦炎。鼻窦炎的诊断是暂时的,应早期通过重复X线检查和活检重新评估,尤其是在存在持续性面部和眼部疼痛的情况下。在开具CT扫描检查单时,必须特别要求对鼻窦底部和颅骨进行扫描,因为常规脑部CT扫描不评估这些区域。4例使用麻醉药无法缓解顽固性疼痛的患者中,有2例使用顺铂后疼痛缓解。