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杏仁核对大鼠视前内侧区的胆碱能激活作用与排卵

Cholinergic activation of medial preoptic area by amygdala for ovulation in rat.

作者信息

Bagga N, Chhina G S, Kumar V M, Singh B

出版信息

Physiol Behav. 1984 Jan;32(1):45-8. doi: 10.1016/0031-9384(84)90068-4.

DOI:10.1016/0031-9384(84)90068-4
PMID:6718533
Abstract

Ovulation blocked by amygdalar lesion was restored by carbachol injection into medial preoptic area (mPOA) in rats on the afternoon of proestrus. Both spontaneous and carbachol-induced ovulation was blocked by application of nicotinic and muscarinic cholinergic antagonists (mecamylamine and atropine) to mPOA. The effect was more pronounced in the latter case. The study suggests amygdalar facilitatory control of ovulation to be mediated via mPOA through the involvement of cholinergic mechanisms.

摘要

在动情前期下午,向大鼠内侧视前区(mPOA)注射卡巴胆碱可恢复因杏仁核损伤而受阻的排卵。向mPOA应用烟碱能和毒蕈碱能胆碱能拮抗剂(美加明和阿托品)可阻断自发排卵和卡巴胆碱诱导的排卵。后一种情况下效果更明显。该研究表明,杏仁核对排卵的促进性控制是通过mPOA经由胆碱能机制介导的。

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Cholinergic activation of medial preoptic area by amygdala for ovulation in rat.杏仁核对大鼠视前内侧区的胆碱能激活作用与排卵
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