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甲基对硫磷毒性作用下莫桑比克罗非鱼组织脂质谱的变化——一项时间进程研究

Changes in the tissue lipid profiles of fish (Oreochromis mossambicus) during methyl parathion toxicity--a time course study.

作者信息

Prasada Rao K S, Ramana Rao K V

出版信息

Toxicol Lett. 1984 May;21(2):147-53. doi: 10.1016/0378-4274(84)90198-x.

Abstract

The levels of total lipids, phospholipids, free fatty acids and total cholesterol were studied in selected tissues of the fish, Oreochromis mossambicus under sublethal stress of methyl parathion for 48 h. The levels of total lipids and phospholipids decreased while the free fatty acids and total cholesterol levels increased during the exposure period. These results are discussed in relation to induced gluconeogenesis and the diversion of acetyl CoA to cholesterol synthesis during methyl parathion intoxication.

摘要

在甲基对硫磷亚致死胁迫48小时的条件下,对莫桑比克罗非鱼特定组织中的总脂质、磷脂、游离脂肪酸和总胆固醇水平进行了研究。在暴露期间,总脂质和磷脂水平下降,而游离脂肪酸和总胆固醇水平上升。结合甲基对硫磷中毒期间诱导的糖异生作用以及乙酰辅酶A向胆固醇合成的转移对这些结果进行了讨论。

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