Prasada Rao K S, Ramana Rao K V
Toxicol Lett. 1984 Jan;20(1):53-7. doi: 10.1016/0378-4274(84)90182-6.
The activity levels of aspartate aminotransferase (AAT), alanine aminotransferase (AlAT) and total adenosine triphosphatase (ATPase) were studied in muscle, gill, liver and brain tissues of control and methyl parathion exposed (MPE) fish. Both aminotransferases were elevated in all the tissues inferring the diversion of alpha-amino acids into the TCA cycle as keto acids to augment energy production during methyl parathion (MP) stress. In gill, liver and brain tissues, there seemed to be a shift in the aminotransferase reactions under MP impact. The total ATPase activity was decreased in all tissues, suggesting inhibition of active transport and oxidative phosphorylation.
在对照鱼和暴露于甲基对硫磷（MPE）的鱼的肌肉、鳃、肝脏和脑组织中，研究了天冬氨酸转氨酶（AAT）、丙氨酸转氨酶（AlAT）和总三磷酸腺苷酶（ATPase）的活性水平。两种转氨酶在所有组织中均升高，这意味着α-氨基酸作为酮酸进入三羧酸循环，以在甲基对硫磷（MP）胁迫期间增加能量产生。在鳃、肝脏和脑组织中，在MP影响下转氨酶反应似乎发生了转变。所有组织中的总ATPase活性均降低，表明主动运输和氧化磷酸化受到抑制。
