LLuis C N, Pérez M G, Balea F D, Santos A C, Figueroa A A
Kardiologiia. 1978 Apr;18(4):90-3.
Arrhythmias were studied at the early stage after rapid ligation of the left ventricular artery on an experimental model of arrhythmia in rabbits. The rabbits were subjected to thoractomy and ligation of the left ventricular artery under direct visualization. The electrocardiographic and hemodynamic parameters were recorded. Electrocardiographic signs of infarction and changes in rhythm were recorded in 60% of the animals. The rate of cardiac contractions and the arterial pressure decreased after the ligation. In the group in which practolol was applied the rate of arrhythmias dropped to 25%. The effect of adrenergic beta-block on acute occlusion of the coronary artery is discussed.
在兔心律失常实验模型中，于快速结扎左心室动脉后的早期阶段对心律失常进行了研究。对兔子进行开胸手术，并在直视下结扎左心室动脉。记录心电图和血流动力学参数。60%的动物记录到梗死的心电图征象和节律变化。结扎后心脏收缩率和动脉压下降。在应用心得宁的组中，心律失常发生率降至25%。讨论了肾上腺素能β受体阻滞剂对冠状动脉急性闭塞的作用。
