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[闭式二尖瓣交界切开术的血流动力学和超声心动图长期结果]

[Hemodynamic and echocardiographic long-term results of closed mitral commissurotomy].

作者信息

Reifart N, Kunkel B, Baykut D, Kaltenbach M, Satter P

出版信息

Z Kardiol. 1984 Mar;73(3):164-72.

PMID:6719994
Abstract

During recent years open mitral commissurotomy (OMC) has seemed to be more favorable than closed commissurotomy (CMC). Up to now only few long-term results including hemodynamic data of mitral valve reconstruction have been reported. 69 of the 103 patients who underwent CMC between 1973 and 1980 were followed over a mean period of 5.3 +/- 2.1 years after intervention. 5 patients died. In 8 (11%) a prosthetic valve replacement was necessary (restenosis 4, insufficiency 2, combined valve disease 2). 36 of the patients were clinically improved (at least 1 NYHA class), 21 (30%) maintained the same NYHA class, and 7 (10%) had deteriorated. The relative heart volume (HV) from supine chest X-rays decreased from 1010 ml/1.71 m2 to 906 ml/1.73 m2 (n = 42, p less than 0.01). The mitral valve area ( MOFL ; n = 25) increased from 1.2 cm2 (Gorlin formula) to 2.6 cm2 (2D-echo) (p less than 0.001). Mean pulmonary artery pressure ( MPAP ) at rest decreased by 29% (from 33.6 mm Hg to 23.8 mm Hg, n = 37, p less than 0.001) and during exercise by 36% (from 69.5 mm Hg to 44.8 mm Hg, n = 10, p less than 0.01). The reduction in PA pressures and the increase in mitral valve area did not correlate and showed no relationship to the intraoperatively estimated success of commissurotomy. Our findings reflect very satisfactory long-term results after closed commissurotomy, which are comparable with those of open valvotomy.

摘要

近年来,直视二尖瓣交界切开术(OMC)似乎比闭式交界切开术(CMC)更具优势。到目前为止,仅有少数包含二尖瓣重建血流动力学数据的长期结果被报道。1973年至1980年间接受CMC的103例患者中,69例在干预后平均随访了5.3±2.1年。5例患者死亡。8例(11%)需要进行人工瓣膜置换(再狭窄4例,关闭不全2例,联合瓣膜病2例)。36例患者临床症状改善(至少提高1个纽约心脏病协会(NYHA)心功能分级),21例(30%)维持相同的NYHA心功能分级,7例(10%)病情恶化。仰卧位胸部X线片测得的相对心脏容积(HV)从1010 ml/1.71 m²降至906 ml/1.73 m²(n = 42,p<0.01)。二尖瓣面积(MOFL;n = 25)从1.2 cm²(戈林公式)增加至2.6 cm²(二维超声心动图)(p<0.001)。静息时平均肺动脉压(MPAP)下降了29%(从33.6 mmHg降至23.8 mmHg,n = 37,p<0.001),运动时下降了36%(从69.5 mmHg降至44.8 mmHg,n = 10,p<0.01)。肺动脉压的降低和二尖瓣面积的增加不相关,且与术中评估的交界切开术成功率无关。我们的研究结果表明,闭式交界切开术后的长期结果非常令人满意,与直视瓣膜切开术的结果相当。

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