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[医源性组织病理学发现。系统汇编]

[Iatrogenic histopathological findings. A systematic compilation].

作者信息

Vock R

出版信息

Z Rechtsmed. 1984;92(1):1-25. doi: 10.1007/BF02116371.

Abstract

A series of drugs and diagnostic agents are deposited (mostly in a metabolized form) in various human organs or cause characteristic histological pictures there. These iatrogenic alterations can frequently be recognized even after a short time and can be demonstrated for varying lengths of time. They may become relevant in various respects in terms of forensic medicine: (1) as an aid to identification in unknown cadavers or cadaver parts, (2) in establishing iatrogenic damage, (3) as an evaluation of findings in sudden and unexpected death from natural causes, and (4) in problems of insurance law with regard to morphological demonstration of chronic drug abuse, especially abuse of analgesics. In a systematic review broken down according to organs, a series of these drugs or diagnostic agents are presented with the morphological alterations they caused, the methods of histological demonstration and the duration of identifiability.

摘要

一系列药物和诊断剂会沉积在(大多以代谢形式)人体的各个器官中,或在这些器官中引起特征性的组织学图像。即使在短时间后,这些医源性改变也常常能够被识别出来,并且能够在不同时长内得到证实。它们在法医学的各个方面可能会变得具有相关性:(1)作为识别无名尸体或尸体部分的辅助手段;(2)用于确定医源性损伤;(3)作为对自然原因导致的突然和意外死亡的调查结果的评估;(4)在保险法问题中,涉及慢性药物滥用,尤其是镇痛药滥用的形态学证明。在一项按器官分类的系统综述中,列出了一系列此类药物或诊断剂及其所引起的形态学改变、组织学证明方法和可识别持续时间。

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