Khaw K T, Barrett-Connor E
Am J Clin Nutr. 1984 Jun;39(6):963-8. doi: 10.1093/ajcn/39.6.963.
A population based study of 685 men and women aged 20 to 79 yr in a predominantly Caucasian community in Southern California found dietary potassium intake estimated from 24-h recall dietary history to be significantly and negatively correlated with age-adjusted systolic pressure in both men and women and with age-adjusted diastolic blood pressure in men. These correlations remained after exclusion of persons taking antihypertension medication or those with categorical hypertension (blood pressure greater than 160/95), and also persisted after adjusting for other dietary variables including alcohol and calcium intake. In women, correlations with blood pressure increased after excluding those taking sex hormones, suggesting that hormonal status may be an important determinant of blood pressure in women and may obscure other relationships. These findings support the etiological relationship of dietary potassium with blood pressure in populations.
在南加州一个以白种人为主的社区,对685名年龄在20至79岁之间的男性和女性进行了一项基于人群的研究。结果发现,根据24小时饮食回顾得出的膳食钾摄入量,与男性和女性经年龄调整的收缩压均呈显著负相关,与男性经年龄调整的舒张压也呈负相关。在排除服用抗高血压药物的人或患有明确高血压(血压高于160/95)的人之后,这些相关性依然存在,并且在对包括酒精和钙摄入量在内的其他饮食变量进行调整后,相关性仍然持续存在。在女性中,排除服用性激素的人之后,与血压的相关性增强,这表明激素状态可能是女性血压的一个重要决定因素,并且可能掩盖其他关系。这些发现支持了人群中膳食钾与血压之间的病因学关系。