Yee R D, Baloh R W, Honrubia V
Arch Ophthalmol. 1984 May;102(5):723-5. doi: 10.1001/archopht.1984.01040030579023.
A 36-year-old woman had intermittent downbeat nystagmus. Between episodes of downbeat nystagmus, eye movements were normal, except for stationary positional nystagmus and decreased vestibulo-ocular responses (VOR) to rotation. Smooth pursuit, optokinetic nystagmus, and visual-VOR interactions, which are usually impaired in patients with downbeat nystagmus and cerebellar dysfunction, were normal. Computed tomography and findings during a suboccipital craniotomy demonstrated a mild Chiari malformation, type 1. Episodic downbeat nystagmus that is not associated with other ocular motor abnormalities due to cerebellar dysfunction can be an initial sign of a Chiari malformation.
一名36岁女性患有间歇性下跳性眼球震颤。在下跳性眼球震颤发作期间，除了静态位置性眼球震颤和旋转时前庭眼反射（VOR）减弱外，眼球运动正常。平稳跟踪、视动性眼球震颤以及视觉 - VOR相互作用通常在患有下跳性眼球震颤和小脑功能障碍的患者中受损，但在该患者中正常。计算机断层扫描和枕下开颅手术中的发现显示为轻度1型Chiari畸形。由于小脑功能障碍导致的与其他眼球运动异常无关的发作性下跳性眼球震颤可能是Chiari畸形的初始体征。
