Coakes R L, Siah P B
Br J Ophthalmol. 1984 Jun;68(6):393-7. doi: 10.1136/bjo.68.6.393.
The immediate effects of topical salbutamol, a beta 2 adrenergic agonist, on the aqueous humour dynamics of 22 normal subjects was studied by fluorophotometry and tonography. Significant lowering of intraocular pressure was accompanied by a significant increase in both aqueous flow rate and tonographic facility of outflow. Uveoscleral outflow was calculated and found to be significantly increased by salbutamol. This appeared to be the predominant acute pressure lowering effect of beta receptor stimulation in the normal human eye.
通过荧光光度法和眼压描记法，研究了β2肾上腺素能激动剂局部应用沙丁胺醇对22名正常受试者房水动力学的即时影响。眼压显著降低的同时，房水流出率和眼压描记法测量的房水流畅系数均显著增加。计算得出葡萄膜巩膜流出量，发现沙丁胺醇可使其显著增加。这似乎是β受体刺激对正常人眼产生急性降眼压作用的主要机制。
